PMID: 6398508Nov 1, 1984Paper

Differences in the etiology of chronic non-alcoholic liver disease in Naples and Copenhagen

Scandinavian Journal of Gastroenterology
C Del Vecchio-BlancoP Schlichting

Abstract

A group of patients with non-alcoholic chronic liver disease from Copenhagen (148) and one from Naples (116) were investigated for the presence of viral and autoimmune serological variables by standardized methods. There were more hepatitis B virus (HBV)-induced cases among the Italians (38.8 versus 15.5%), but the sex ratio and biochemical activity were not different from the Danish ones. Autoimmune markers were much more frequent and in higher titers in Danish HBV-negative patients than in Italian ones. Fewer were women, and thus few Italians fit the theory of autoimmune pathology; rather, their chronic liver disease is caused by other hepatitis viruses than B.

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