Differences in the pathology of the metabolic syndrome with or without visceral fat accumulation: a study in pre-diabetic Japanese middle-aged men.

Endocrine
Yutaka MoriNaoko Tajima

Abstract

To elucidate the role of visceral fat accumulation in the metabolic syndrome, differences in the pathology of the metabolic syndrome with or without visceral fat accumulation were investigated. A total of 472 prediabetic Japanese men (mean age, 47.5 +/- 7.2 yr) with impaired fasting glycemia (IFG) levels of 110-125 mg/dL were eligible for participation in the study. The study subjects were divided into the following four groups, and intergroup comparisons were made: group I without visceral fat area [VFA] > or = 100 cm2 but presenting with fewer than two other risk factors (i.e., TG > or =150 mg/dL, HDL-C < 40 mg/dL, BP > or = 130/ > or = 85 mmHg, or FPG > or = 110 mg/dL) (n = 231); group II without VFA of > or = 100 cm2 but presenting with three or more other risk factors (n = 57); group III with VFA of > or = 100 cm2 accompanied by FPG 110 mg/dL alone (n = 27); and group IV with VFA > or =100 cm2 and two or more other risk factors (n = 157). The prevalence of patients who had three or more risk factors with or without VFA > or = 100 cm2 was 45.3% (214 out of 472 patients), while that of those with VFA > or = 100 cm2 who had two or more other risk factors was 33% (157 out of 472 patients). Group II had significantly higher VFA...Continue Reading

Citations

Jun 15, 2007·Journal of Hypertension·Elisabeth LambertGavin Lambert
Mar 5, 2011·Current Osteoporosis Reports·Yahtyng Sheu, Jane A Cauley
Mar 18, 2015·Hormone Molecular Biology and Clinical Investigation·Jonathan DiedrichIzabela Podgorski
Mar 29, 2011·The Tohoku Journal of Experimental Medicine·Mariko InoueEiji Yano
Jun 18, 2009·The Journal of Clinical Endocrinology and Metabolism·Vicente GilsanzSteven D Mittelman
Nov 15, 2013·Mediators of Inflammation·Abdulaziz FarooqVidya Mohamed-Ali
Dec 11, 2007·Anais Da Academia Brasileira De Ciências·Nicolas WiernspergerEliete Bouskela
Apr 11, 2017·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Hong LeiZhenyan Chen

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