Different amounts of alcohol consumption and cataract: a meta-analysis

Optometry and Vision Science : Official Publication of the American Academy of Optometry
Yu GongChen-Wei Pan

Abstract

To evaluate the association between different amounts of alcohol consumption and the risk of age-related cataract. We searched PubMed and Embase from their inception until May 2014 for case-control or cohort studies with data on alcohol consumption and age-related cataract. Heavy alcohol consumption was defined as more than two standard drinks per day, which is equal to a daily intake of 20 g of alcohol or 140 g per week. Moderate consumption was defined as less than 20 g of alcohol per day but more than never any. We performed separate meta-analyses for the associations of moderate or heavy alcohol consumption with age-related cataract under a random-effects model, respectively. Five case-control and five cohort studies were identified through comprehensive literature search. In the meta-analysis of 10 studies, the associations between moderate alcohol consumption and age-related cataract were marginally nonsignificant (pooled relative risk, 0.88; 95% confidence interval, 0.74 to 1.05; I = 82.1%), whereas heavy alcohol consumption was associated with an increased risk of age-related cataract (pooled relative risk, 1.26; 95% confidence interval, 1.06 to 1.50; I = 58.9%). The association between heavy alcohol consumption and cat...Continue Reading

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Oct 4, 2015·Journal of Diabetes and Its Complications·Eva K FenwickEcosse L Lamoureux
Jun 29, 2017·Ophthalmic Epidemiology·Sangshin Park, Nam-Kyong Choi
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