PMID: 9920Jan 1, 1976

Different behaviour of thymus in hosts bearing skin homografts or ehrlich ascites carcinoma

Archiv für Geschwulstforschung
G SimuD Nestor

Abstract

Thymus behaviour in A2G male mice transplanted with skin homografts or Ehrlich ascites carcinoma was followed for a period of 28 days. In comparison with control mice of the same strain in which only a slowly physiological involution of the thymus was observed, a marked, irreversible involution was seen in the tumour-bearing mice in contrast with the transient, completely recovered involution in animals transplanted with skin homografts. Thymus behaviour appears as the major structural difference between a host developping a strongly efficient or an inefficient immune response.

Related Concepts

Tumor Antibodies
Antibody Formation
Carcinoma, Ehrlich Tumor
Graft Vs Host Reaction
Mice, Inbred CBA
Neoplasm Transplantation
Thymus Gland
Transplantation, Homologous
Skin Transplantation

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