Abstract
The purpose of the present study was to review the different clinical manifestations of primary gastrointestinal (GI) malignancies and benign tumors in pediatric patients. The demographic data, duration to diagnosis, clinical features, laboratory data, location and pathology of the tumors, and outcomes of pediatric patients from January 1984 to December 2009 were retrospectively reviewed. A total of 24 GI malignancies and 62 benign tumors were diagnosed. Patients in the benign group were mostly diagnosed in the first decade of life (73%), whereas majority of patients with malignancies were older than 10 years (79%). The most common tumor location in the benign group was the colorectum, whereas in the malignant group, tumors were distributed equally in the small intestine and colorectum. The median duration from onset to diagnosis in the benign group was longer than that of the malignant group (P>00.05). There was statistically significant increase in the presence of hematochezia in patients with benign tumor compared with those with malignancy (P<00.05). Among the malignancies, 79% presented with abdominal pain, followed by weight loss (25%), anorexia (25%), palpable mass (25%), and fever (21%), with statistically significant d...Continue Reading
References
Aug 31, 1978·The New England Journal of Medicine·H J WaneboH F Oettgen
Mar 15, 1992·Cancer·C A AngelI D Fleming
Apr 1, 1991·Journal of Pediatric Gastroenterology and Nutrition·T TaguchiK Ueda
Dec 1, 1988·Histopathology·J R JassB C Morson
Feb 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S B MurphyC W Berard
Aug 1, 1986·The Surgical Clinics of North America·J F Goldthorn, P C Canizaro
Feb 1, 1967·Pediatric Clinics of North America·L K Pickett, H C Briggs
Apr 1, 1984·Annals of Surgery·N WolmarkP Jochimsen
May 1, 1980·Annals of Surgery·K ContrearyW F Becker
Jul 1, 1994·Annals of Surgical Oncology·M A SkinnerL R Scherer
May 9, 1996·The New England Journal of Medicine·J T SandlundW M Crist
Jul 1, 1997·Journal of Pediatric Surgery·C A BethelD R Cooney
May 9, 2001·The Journal of Pediatrics·J CorredorJ Barnard
Jan 18, 2005·Journal of Pediatric Hematology/oncology·Guillermo L ChantadaFelipe Gustavo Gercovich
Feb 7, 2006·Seminars in Pediatric Surgery·Alan P Ladd, Jay L Grosfeld
Mar 23, 2006·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Thomas M Attard, Rosemary J Young
Jan 27, 2007·Journal of Pediatric Gastroenterology and Nutrition·Dragan KravarusicEnrique Freud
Feb 17, 2007·Gut·Lodewijk A A BrosensFrancis M Giardiello
Apr 4, 2007·Pediatric Blood & Cancer·Andrea FerrariGianfranco Gallino
Apr 14, 2007·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·C A Durno
Jan 9, 2008·Diseases of the Colon and Rectum·Olof JannaschFrank Meyer
Feb 6, 2008·Pediatric Surgery International·Saleem IslamJames D Geiger
May 6, 2008·Paediatric Drugs·Raya Saab, Wayne L Furman
Aug 5, 2008·Journal of Pediatric Surgery·Jennifer L CurtisHenri R Ford
Nov 18, 2008·Journal of Pediatric Hematology/oncology·Anna Maria BuccolieroGian Luigi Taddei
Mar 17, 2009·The Journal of Surgical Research·Relin YangJuan E Sola
Mar 28, 2009·Journal of Pediatric Gastroenterology and Nutrition·John Barnard
Jun 30, 2009·The Journal of Surgical Research·Ying ZhugeJuan E Sola
Feb 16, 2010·Journal of Pediatric Surgery·Martin Louis van NiekerkTomas Slavik