Different Diagnosis, Shared Vulnerabilities: The Value of Cross Disorder Validation of Capacity to Consent

Journal of Alzheimer's Disease : JAD
Allyson Rosen, Julie C Weitlauf

Abstract

A screening measure of capacity to consent can provide an efficient method of determining the appropriateness of including individuals from vulnerable patient populations in research, particularly in circumstances in which no caregiver is available to provide surrogate consent. Seaman et al. (2015) cross-validate a measure of capacity to consent to research developed by Jeste et al. (2007). They provide data on controls, caregivers, and patients with mild cognitive impairment and dementia. The study demonstrates the importance of validating measures across disorders with different domains of incapacity, as well as the need for timely and appropriate follow-up with potential participants who yield positive screens. Ultimately clinical measures need to adapt to the dimensional diagnostic approaches put forward in DSM 5. Integrative models of constructs, such as capacity to consent, will make this process more efficient by avoiding the need to test measures in each disorder. Until then, cross-validation studies, such as the work by Seaman et al. (2015) are critical.

References

Jan 7, 2005·Journal of Traumatic Stress·Elana Newman, Danny G Kaloupek
Aug 8, 2007·Archives of General Psychiatry·Dilip V JesteHelena C Kraemer
May 17, 2008·Journal of the American Geriatrics Society·Angela L JeffersonJason H Karlawish
Jun 1, 2007·Journal of Empirical Research on Human Research Ethics : JERHRE·Julie C WeitlaufJennifer Keller
Mar 1, 2007·Journal of Empirical Research on Human Research Ethics : JERHRE·Julie Weitlauf
Jan 19, 2010·Research in Gerontological Nursing·Ann M Mayo, Margaret I Wallhagen
Sep 3, 2013·The Journal of Nervous and Mental Disease·Michael B First
Mar 15, 2015·Journal of Alzheimer's Disease : JAD·Jennifer Burgher SeamanJennifer Hagerty Lingler

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