Different morbidity after pneumonectomy: multidrug-resistant tuberculosis versus non-tuberculous mycobacterial infection

Interactive Cardiovascular and Thoracic Surgery
Yuji ShiraishiMiyako Hiramatsu

Abstract

To assess whether there is any difference in postoperative morbidity and mortality after pneumonectomy between patients with multidrug-resistant tuberculosis (MDR-TB) and patients with non-tuberculous mycobacterial (NTM) infections. Between January 2000 and December 2007, 61 patients with MDR-TB and 60 patients with NTM infections underwent 66 and 64 pulmonary resections, respectively. Of these, 33 patients were analyzed who underwent a pneumonectomy, including 22 patients with MDR-TB (seven right, 15 left) and 11 patients with NTM infections (seven right, four left). All bronchial stumps were covered with the latissimus dorsi. Patients with NTM infections were predominantly more female, older, thinner, and presented with a higher frequency of culture-positive sputum at operation than patients with MDR-TB. Operative mortality was zero. Morbidities were bronchial stump dehiscence (n=1) and mycobacterial empyema (n=1) for patients with MDR-TB, and acute respiratory failure (n=1), bronchial stump dehiscence (n=5) and mycobacterial empyema (n=2) for patients with NTM infections. Prevalence of bronchial stump dehiscence was significantly higher in patients with NTM infections (P=0.010). Five of six dehiscences occurred after right p...Continue Reading

References

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Citations

Jul 12, 2014·Revue des maladies respiratoires·P MordantF Le Pimpec-Barthes
Jul 3, 2013·The Medical Clinics of North America·John B Lynch
Oct 12, 2019·Interactive Cardiovascular and Thoracic Surgery·Igor Ya MotusAnna S Tsvirenko
Apr 12, 2021·The Annals of Thoracic Surgery·Takeo TogoYuji Shiraishi

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