PMID: 11925400Apr 2, 2002Paper

Different perspectives of patients and health care professionals on the potential benefits and risks of blastocyst culture and multiple embryo transfer

Human Reproduction
G M Hartshorne, R J Lilford

Abstract

A trade-off exists between the risk of multiple pregnancy and prospects of pregnancy itself in assisted reproduction. Blastocyst culture and embryo transfer after approximately 5 days may be one method of reconciling this dilemma, although a controversial one. We presented a questionnaire to groups of patients, embryologists and clinicians to solicit views on the potential benefits and risks of blastocyst culture and multiple pregnancy. The results indicate that patients are more accepting of multiple pregnancy as a prospective outcome of treatment than those involved in their treatment, despite awareness of the risks. Our data tend to support a genuine difference in values on this point. We also sought views on the patient selection criteria and treatment protocols which should apply in a planned randomized controlled trial comparing blastocyst culture with cleaving embryo transfer (e.g. numbers of embryos to transfer, acceptable levels of risk of twin and triplet pregnancy, the proportion of patients who would be put off from entering the trial by the risk of no embryo transfer). These are presented and discussed with reference to their likely impact on trial recruitment, highlighting differences in perspective between patien...Continue Reading

Citations

Sep 26, 2009·Journal of Assisted Reproduction and Genetics·Fabrice GuerifDominique Royere
Mar 24, 2004·Fertility and Sterility·David Adamson, Valerie Baker
Mar 24, 2004·Fertility and Sterility·Cris GlazebrookGeorge Ndukwe
Oct 15, 2003·Fertility and Sterility·Juan R Correa-Pérez, René Fernández-Pelegrina
Nov 14, 2012·Human Reproduction·A Maheshwari, S Bhattacharya
Jun 1, 2005·The Journal of Perinatal & Neonatal Nursing·Kim L Armour, Lynn Clark Callister
Nov 18, 2011·Human Fertility : Journal of the British Fertility Society·Allan A Pacey, Christine Eiser
Feb 10, 2010·Human Fertility : Journal of the British Fertility Society·Brenda Leese, Jane Denton
May 21, 2013·Fertility and Sterility·Christopher NewtonVeronica Asgary-Eden
Nov 14, 2006·Fertility and Sterility·Christopher R NewtonStephen Power
Jun 21, 2007·BJOG : an International Journal of Obstetrics and Gynaecology·G S ScotlandS Bhattacharya
Nov 12, 2013·Computers in Biology and Medicine·G CoraniL M Gambardella
Jul 31, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A UmranikarS Fountain
Oct 30, 2004·Human Reproduction Update·Jan M R Gerris
Jun 24, 2006·Human Reproduction·M van WelyF van der Veen
May 21, 2005·Human Reproduction·Maureen Porter, Siladitya Bhattacharya
Oct 1, 2010·Reproductive Biomedicine Online·Elisabet CluaAnna Veiga

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