Different predictive values of electrophysiological testing and autonomic assessment in patients surviving a sustained arrhythmic episode

Circulation Journal : Official Journal of the Japanese Circulation Society
Grzegorz RaczakGrazyna Swiatecka

Abstract

Recent data suggest that the electrophysiological study (EPS) has limited value in the identification of high risk patients, so the aim of the present study was to evaluate if non-invasive measurement of baroreflex sensitivity (BRS), a marker of autonomic balance, provides additional prognostic information in patients surviving a sustained arrhythmic episode. The study group comprised 112 post myocardial infarction patients consecutively referred for EPS following documented ventricular fibrillation (VF) (20), sustained ventricular tachycardia (VT) (74) or a syncopal episode with subsequently documented non-sustained VT at Holter monitoring (18). BRS was assessed according to the transfer function method. A cardioverter - defibrillator (ICD) was implanted in 97 patients. During follow-up (median 315 days), appropriate ICD discharge occurred in 53 patients, and 3 more patients died suddenly. Sustained VT was induced in 84% and 77% of patients who did or did not develop arrhythmia at follow-up (p=0.34). No differences were found in age, sex, infarct site, drug therapy, resting RR interval or cycle of induced VT. Left ventricular ejection fraction (LVEF) < or =35%, New York Heart Association (NYHA) class >2 and BRS < or =3.3 ms/mm...Continue Reading

References

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Citations

Apr 26, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Hiroshi WatanabeYoshifusa Aizawa
Jan 24, 2007·Pacing and Clinical Electrophysiology : PACE·Robert BauernschmittRüdiger Lange
Feb 28, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Masaru YugeTohru Izumi

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