Different shades of default mode disturbance in schizophrenia: Subnodal covariance estimation in structure and function

Human Brain Mapping
Jérémy Lefort-BesnardDanilo Bzdok

Abstract

Schizophrenia is a devastating mental disease with an apparent disruption in the highly associative default mode network (DMN). Interplay between this canonical network and others probably contributes to goal-directed behavior so its disturbance is a candidate neural fingerprint underlying schizophrenia psychopathology. Previous research has reported both hyperconnectivity and hypoconnectivity within the DMN, and both increased and decreased DMN coupling with the multimodal saliency network (SN) and dorsal attention network (DAN). This study systematically revisited network disruption in patients with schizophrenia using data-derived network atlases and multivariate pattern-learning algorithms in a multisite dataset (n = 325). Resting-state fluctuations in unconstrained brain states were used to estimate functional connectivity, and local volume differences between individuals were used to estimate structural co-occurrence within and between the DMN, SN, and DAN. In brain structure and function, sparse inverse covariance estimates of network coupling were used to characterize healthy participants and patients with schizophrenia, and to identify statistically significant group differences. Evidence did not confirm that the backb...Continue Reading

References

Aug 8, 1987·The Journal of Comparative Neurology·B A Vogt, D N Pandya
Oct 1, 1981·Annals of Neurology·M M Mesulam
Jan 1, 1995·Journal of Neurophysiology·K M StephanR S Frackowiak
Jan 23, 1995·Behavioural Brain Research·B HorwitzC L Grady
May 1, 1996·Psychological Medicine·C D Frith, R Corcoran
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·M E RaichleG L Shulman
Dec 31, 2002·Biological Psychology·Yasuharu SatoSunao Kaneko
Dec 31, 2002·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Jun 13, 2003·Neuroreport·Patrick HaggardNicolas Franck
Jan 23, 2004·Nature·Bogdan DraganskiArne May
Jun 16, 2005·NeuroImage·John Ashburner, Karl J Friston
Jan 10, 2006·Brain : a Journal of Neurology·Andrea E Cavanna, Michael R Trimble
May 30, 2006·Neuron·Nico U F DosenbachSteven E Petersen
Sep 9, 2006·Nature Medicine·David A Lewis, Guillermo Gonzalez-Burgos
Mar 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·William W SeeleyMichael D Greicius
Mar 3, 2007·The American Journal of Psychiatry·Abigail G GarrityVince D Calhoun
May 9, 2007·Schizophrenia Bulletin·Andreas Konrad, Georg Winterer
Jul 14, 2007·Schizophrenia Research·Yuan ZhouTianzi Jiang
Aug 21, 2007·Nature Reviews. Neuroscience·Michael D Fox, Marcus E Raichle
Nov 10, 2007·Proceedings of the National Academy of Sciences of the United States of America·Hanbing LuElliot A Stein
Dec 15, 2007·Biostatistics·Jerome FriedmanRobert Tibshirani
Dec 28, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Demis HassabisEleanor A Maguire
Feb 13, 2008·Journal of Abnormal Psychology·Arnaud D'ArgembeauMartial Van der Linden
Feb 27, 2008·Brain : a Journal of Neurology·Yong LiuTianzi Jiang
Apr 1, 2008·Biological Psychiatry·Steven J Luck, James M Gold
Apr 11, 2008·Annals of the New York Academy of Sciences·Randy L BucknerDaniel L Schacter
Oct 1, 2008·Neuroscience and Biobehavioral Reviews·Samantha J BroydEdmund J S Sonuga-Barke
Dec 2, 2008·Schizophrenia Bulletin·S G PotkinUNKNOWN FBIRN
Jan 22, 2009·Schizophrenia Bulletin·Klaas E StephanChris D Frith
Jan 24, 2009·Proceedings of the National Academy of Sciences of the United States of America·Susan Whitfield-GabrieliLarry J Seidman
Feb 4, 2009·Proceedings of the National Academy of Sciences of the United States of America·C J HoneyP Hagmann
Nov 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Daniel S MarguliesMichael Petrides
Nov 19, 2009·Schizophrenia Bulletin·Jazmin CamchongKelvin O Lim
Jan 26, 2010·Schizophrenia Research·Anna Rotarska-JagielaDavid E J Linden
Feb 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·D C GlahnJ Blangero
Mar 2, 2010·Neuron·Jessica R Andrews-HannaRandy L Buckner
Mar 3, 2010·Brain : a Journal of Neurology·R L Carhart-Harris, K J Friston
Jun 1, 2010·Brain Structure & Function·Vinod Menon, Lucina Q Uddin
Jun 18, 2010·Psychiatry Research·Dost OngürPerry F Renshaw

❮ Previous
Next ❯

Citations

Aug 3, 2018·Nature Communications·Cedric Huchuan XiaTheodore D Satterthwaite
Mar 18, 2020·Network Neuroscience·Paria RezaeiniaR McKell Carter
May 28, 2021·Cognitive Neurodynamics·Zhongyang WangWei Qian
Feb 2, 2018·NeuroImage. Clinical·Eithan KotkowskiPeter T Fox
Aug 12, 2021·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Ilja M J SarisUNKNOWN PRISM consortium

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.