Different substrates of non-sustained ventricular tachycardia in post-infarction patients with and without left ventricular dilatation

Journal of Cardiac Failure
Gianluca Di BellaAlessandro Pingitore

Abstract

We investigated the relationship between nonsustained ventricular tachycardia (NSVT) and left ventricular (LV) dilatation, function, remodeling, and scar tissue extent in patients with previous myocardial infarction (MI). Eighty-two patients (ages 64+/-10 years) with first previous MI were referred for 24-hour electrocardiogram recording and cine and delayed enhancement (DE) cardiac magnetic resonance (CMR). LV volumes, ejection fraction, systolic wall thickening, sphericity index, and core and peri-infarctual areas of scar tissue by CMR were evaluated. LV dilatation was observed in 39 patients. Episodes of NSVT were recorded in 32 patients: 23 with LV dilatation and 9 without. In the entire population, NSVT was related to ejection fraction, LV volumes, LV mass, and sphericity index; end-systolic volume (P=.001) resulted in the only independent predictor at multivariate analysis. In patients without LV dilatation, the occurrence of NSVT was only positively related with percentage of contracting segments with DE (P=.008). Conversely, in patients with LV dilatation, increase in LV mass (P=.020) and end-systolic volume (P=.038) were independent predictors of NSVT. Necrotic and viable myocardium coexistence within the same wall seg...Continue Reading

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Citations

Nov 10, 2010·The International Journal of Cardiovascular Imaging·E E van der WallM J Schalij
Oct 23, 2012·Journal of the American College of Cardiology·Demosthenes G KatritsisA John Camm
Dec 24, 2010·World Journal of Cardiology·Gianluca Di Bella

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