Different types of childhood adversity and 5-year outcomes in a longitudinal cohort of first-episode psychosis patients.

Psychiatry Research
Olesya AjnakinaHelen L Fisher

Abstract

Little is known about the impact of different forms of childhood adversity on outcomes in first-episode psychosis (FEP) patients beyond the first year of treatment. We investigated associations between different types of childhood adversity and outcomes of FEP patients over the 5 years following their first contact with mental health services for psychosis. 237 FEP cases aged 18-65 years were followed on average for 5 years after first presentation to psychiatric services in South London, UK. Childhood adversity prior to 17 years of age was assessed at baseline using the Childhood Experience of Care and Abuse Questionnaire (CECA.Q). The results showed that exposure to at least one type of childhood adversity was significantly associated with a lower likelihood of achieving symptomatic remission, longer inpatient stays, and compulsory admission over the 5-year follow-up. There was no evidence though of a dose-response effect. Some specificity was evident. Childhood parental separation was associated with significantly greater likelihood of non-compliance with antipsychotic medications, compulsory admission, and substance dependence. Institutional care was significantly associated with longer total length of inpatient stays; and ...Continue Reading

Citations

May 7, 2020·European Journal of Psychotraumatology·Esther Setién-SueroRosa Ayesa-Arriola
Apr 16, 2019·Frontiers in Neuroscience·David PopovicPeter Falkai
Jan 27, 2021·Development and Psychopathology·Daniela MarchettiGiorgio Falgares
Aug 28, 2021·Early Intervention in Psychiatry·Shi Hyun KangYoung Chul Chung
Nov 4, 2021·European Psychiatry : the Journal of the Association of European Psychiatrists·Ana CatalanPaolo Fusar-Poli
Jan 25, 2022·The International Journal of Social Psychiatry·Anna ButjosaUNKNOWN PEPs Group

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