PMID: 8614570Nov 17, 1995Paper

Differential cellular localization of oestrogen receptor immunoreactivity and oxytocin mRNA and immunoreactivity in the rat preoptic area

Neuroscience Letters
C J CruttwellR J Bicknell

Abstract

Oestrogen influences both oxytocin mRNA and peptide immunoreactivity in the preoptic area and the rat oxytocin gene contains functional oestrogen response elements. However, using combinations of immunocytochemistry and in situ hybridization for oxytocin and oestrogen receptor, we found that preoptic oxytocin neurons do not possess oestrogen receptors. This finding implies oestrogen actions on oxytocin synthesis in preoptic neurones are unlikely to be mediated directly.

References

Jun 12, 1992·Annals of the New York Academy of Sciences·D T Theodosis, D A Poulain
Jun 12, 1992·Science·D L LefebvreH H Zingg
Apr 1, 1991·Physiological Reviews·P RichardM J Freund-Mercier
Apr 1, 1988·Neuroscience·G F JirikowskiW E Stumpf
Jun 1, 1987·The Journal of Physiology·J C Randle, L P Renaud
Jun 1, 1985·The Journal of Endocrinology·T HiguchiK Wakabayashi
Apr 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·R Ivell, D Richter
Sep 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·G L GreeneE V Jensen
May 7, 1982·Science·C A PedersenA J Prange
Aug 1, 1989·Journal of Neuroendocrinology·J D CaldwellC A Pedersen
Oct 1, 1990·Journal of Neuroendocrinology·J PeterG Ab

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Citations

Sep 7, 2000·Neuroscience·G P Cardona-GómezL M Garcia-Segura

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