Differential cigarette-related startle cue reactivity among light, moderate, and heavy smokers.

Addictive Behaviors
Yong CuiPaul M Cinciripini

Abstract

In this study, we examined the relationship between the level of daily cigarette consumption and the startle response to affective and cigarette-related cues among treatment-seeking smokers. Before receiving any behavioral or pharmacological treatment, 136 smokers attended a baseline laboratory session, during which we recorded their reflexive eyeblink responses to acoustic startle probes while they were viewing pleasant, unpleasant, neutral, and cigarette-related pictures. We found that 1) cigarette-related and pleasant pictures similarly reduced the startle magnitude compared to neutral pictures; 2) the magnitude of startle modulation rendered by pleasant or unpleasant pictures did not differ among light, moderate, and heavy smokers; and 3) startle attenuation by cigarette-related pictures was greater in heavy smokers than in light smokers. These results suggest that similar to pleasant stimuli, cigarette-related cues are motivationally salient for smokers, and that this salience increases with nicotine dependence.

Associated Clinical Trials

References

Sep 1, 1988·American Journal of Public Health·T E NovotnyP L Remington
Mar 22, 2002·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·David SatcherJeffrey P Koplan
Mar 14, 2003·Biological Psychology·Joel EllwangerDavid L Braff
Jul 11, 2003·Biological Psychology·Katja LudewigFranz X Vollenweider
Oct 2, 2003·Addiction·Andrew J WatersKarin Mogg
Jan 17, 2004·Psychopharmacology·S Orain-PelissoloR Jouvent
Feb 22, 2005·Psychophysiology·Terry D BlumenthalAnton van Boxtel
May 28, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·F Joseph McClernonJed E Rose
Aug 9, 2005·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·David G GilbertJodi I Huggenvik
Aug 9, 2005·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Jennifer W TideyRobert M Swift
Oct 28, 2005·Nature Neuroscience·John A Dani, R Adron Harris
Apr 7, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Dharma McBrideAlain Dagher
Jun 28, 2006·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Brian L CarterPaul M Cinciripini
Jun 28, 2006·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Paul M CinciripiniDavid W Wetter
Nov 7, 2008·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Ashley B Parker, David G Gilbert
Aug 12, 2009·Addiction·Anne K RehmeMichael Wagner
Jan 15, 2010·Psychophysiology·Francesco VersacePaul M Cinciripini
Jan 22, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bastian StippekohlRudolf Stark
Mar 3, 2010·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Carla J BergJasjit S Ahluwalia
Aug 24, 2010·Biological Psychology·Michela SarloDaniela Palomba
Dec 25, 2010·Addiction Biology·Francesco VersacePaul M Cinciripini

❮ Previous
Next ❯

Citations

Jun 18, 2014·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Jonathan B BrickerJaimee L Heffner
Oct 13, 2012·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Yong CuiPaul M Cinciripini
Feb 26, 2014·Current Opinion in Pharmacology·Massimo BaniChristian Heidbreder
Apr 2, 2021·Frontiers in Psychiatry·Raquel Martín RíosIgnacio Martín Tamayo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.