Differential diagnosis and prognosis of 112 excised epibulbar epithelial tumors

Klinische Monatsblätter für Augenheilkunde
B SeitzG Naumann

Abstract

Epithelial tumors of the epibulbar conjunctiva are rare in northern Europe. There are no reliable clinical criteria to predict the histological nature of the lesion. Even histologically proven malignant tumors typically do not show ocular invasion or metastasis. From 1980 to 1993, 112 epithelial epibulbar tumors were classified in our ophthalmopathological laboratory. Surgical management of 50 papillomas (mean age 46 +/- 18 years, 58% males), 49 conjunctival/corneal intraepithelial neoplasias (CIN) (28 mild, 21 severe) and 12 squamous cell carcinomas (mean age 63 +/- 13 years, 69% males) included excisional biopsy (61%), with additional lamellar keratectomy (14%), epithelial abrasion (10%), cauterisation (3%), cryotherapy (2%), excimer laser ablation (2%). Other management regimes were lamellar keratoplasty (2%), penetrating keratoplasty (2%), epithelial abrasion (2%). One eye with intraocular invasion of a mucoepidermoid carcinoma was enucleated. Fifty five per cent of the papillomas were located at the caruncle or semilunar fold. Seventy eight percent of the papillomas had a pedunculated appearance. Two lesions involved the epibulbar conjunctiva as well as the opposite tarsal conjunctiva ("kissing papilloma"). Eighty eight pe...Continue Reading

Citations

Apr 21, 1999·The British Journal of Ophthalmology·M TuncT Miller
May 29, 2007·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·L M HolbachF E Kruse
Sep 11, 2008·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M S SpitzerH N Batumba
Feb 1, 2009·Journal français d'ophtalmologie·J SudzinskiS Milazzo
Jan 12, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Carlos GarciaElise Fowler
Jul 28, 2005·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·T A FuchslugerD Meller

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