Differential effect of haloperidol and clozapine on plasma homovanillic acid in elderly schizophrenic patients with or without tardive dyskinesia

Biological Psychiatry
I AndíaR Dávila

Abstract

Plasma homovanillic acid (HVA) changes in response to a challenge of several days with haloperidol have been found to be predictive of the therapeutic response to haloperidol over a longer period of treatment. Twenty-six elderly women who gave informed consent were divided into two groups, with or without tardive dyskinesia, and subjected to an 80-day washout, after which both the dyskinetic and nondyskinetic group was divided, and half of each group given haloperidol or clozapine. The nondyskinetic group had a brief rise in plasma HVA, then a decline. The dyskinetic group had no change in plasma HVA. Neither group challenged with clozapine had any change in plasma HVA.

References

Jan 1, 1992·Schizophrenia Bulletin·F AminK L Davis
May 1, 1991·The American Journal of Psychiatry·V Khot, R J Wyatt
Jan 1, 1991·Schizophrenia Bulletin·H Y Meltzer
Jan 1, 1991·Acta Psychiatrica Scandinavica·R DávilaJ Guimón
Oct 1, 1989·Archives of General Psychiatry·J A LiebermanJ M Kane
Aug 1, 1988·Journal of Clinical Psychopharmacology·P Seeman
Jun 1, 1988·Archives of General Psychiatry·R DavilaA J Friedhoff
Jan 1, 1993·Schizophrenia Bulletin·D V Jeste, M P Caligiuri

❮ Previous
Next ❯

Citations

Oct 27, 2007·The Journal of Emergency Medicine·Revital Gandelman-MartonJose Martin Rabey
Dec 20, 2000·Schizophrenia Research·S P YovtchevaJ K Moles
Dec 1, 2005·Progress in Neuro-psychopharmacology & Biological Psychiatry·Jessica Oi-Yin WongAlfert Wai-Kiu Tsang
Sep 8, 2005·Psychosomatics·Neil B SandsonKelly L Cozza
Jul 6, 2000·European Psychiatry : the Journal of the Association of European Psychiatrists·P Batel
Feb 13, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Mercedes ZumárragaJosé Guimón
Feb 7, 2018·The Cochrane Database of Systematic Reviews·Hanna BergmanKarla Soares-Weiser
Jan 27, 2006·The Cochrane Database of Systematic Reviews·R G MarriottS Waddingham

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Related Papers

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
M. MelzerE. L. C. Ong
© 2021 Meta ULC. All rights reserved