Abstract
A canine model was developed to study the differential response of a gram-negative and a gram-positive bacterial infection on autogenous and prosthetic grafts. After replacing segments of the femoral arteries of 15 dogs with autogenous vein in one groin and polytetrafluoroethylene in the contralateral groin, 10(8) colony-forming units of nonmucin-producing Staphylococcus epidermidis (five dogs), Pseudomonas aeruginosa (five dogs), or sterile saline solution (five dogs) were directly inoculated onto the grafts. The grafts were examined 7 to 10 days after implantation. None of the control dogs exhibited inflammatory signs, and no grafts or anastomoses disrupted. S. epidermidis was unrecoverable from either graft material in any of the animals, although histologic evaluation confirmed neutrophils and bacteria in four of five animals in the vein and polytetrafluoroethylene groups. No dog inoculated with S. epidermidis had graft or anastomotic disruption. By contrast, P. aeruginosa was recovered from both types of grafts in all inoculated animals. Neutrophils, bacteria, and microabscesses were observed in all of these animals. In addition, three of five polytetrafluoroethylene grafts and all five vein grafts disrupted either at the ...Continue Reading
References
Mar 1, 1975·The Journal of Surgical Research·W S MooreB Bean
Apr 1, 1978·The Journal of Surgical Research·L H KnottJ B Grogan
Jun 1, 1975·Annals of Surgery·G G JamiesonC G Rob
Mar 1, 1989·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·C E EdmistonG R Seabrook
Sep 1, 1987·Journal of Vascular Surgery·W H EdwardsJ L Mulherin
Nov 1, 1987·Annals of Surgery·J M Harris, L F Martin
Jan 1, 1988·Journal of Vascular Surgery·T M BergaminiJ B Towne
Apr 1, 1985·Canadian Journal of Microbiology·T I Nicas, B H Iglewski
Dec 1, 1988·The Journal of Antimicrobial Chemotherapy·M R BrownP Gilbert
Sep 1, 1972·Annals of Surgery·D E SzilagyiM P Vrandecic
Jun 1, 1972·The Journal of Trauma·N M Rich, C W Hughes
Dec 1, 1970·Chest·D L BrickerM E DeBakey
Nov 1, 1984·Journal of Vascular Surgery·G A MacbethJ M Malone
Jan 1, 1984·Journal of Vascular Surgery·L M ReillyR J Stoney
Jan 1, 1984·Archives of Surgery·D F BandykJ B Towne
May 1, 1984·American Journal of Surgery·K S StoneR W Dunstan
Dec 1, 1982·The Journal of Surgical Research·R E WardT C Flynn
May 1, 1981·Archives of Surgery·J H Kwaan, J E Connolly
Citations
Feb 9, 2000·Journal of Vascular Surgery·K D CalligaroM J Dougherty
Feb 5, 2004·Vascular and Endovascular Surgery·Timothy W SwainMatthew D Dougherty
Nov 21, 2015·Vascular Medicine·Arman KilicYing Wei Lum
Feb 5, 2009·Vascular and Endovascular Surgery·Robert A McCreadyH Reid Mattison
Nov 24, 2006·Annals of Plastic Surgery·Eleonore ZetrenneDeepak Narayan
Mar 29, 2005·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·John A GermillerUdayan K Shah
Dec 3, 1999·The British Journal of Surgery·R T ChalmersS P Barrett
Apr 6, 2013·Surgery Today·Kimihiro IgariYoshinori Inoue
Oct 14, 2011·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Maciej Dryjski, Hasan H Dosluoglu
Jul 3, 2004·ANZ Journal of Surgery·Stefan PonoshKishore Sieunarine
Nov 19, 2011·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J Simkins, V Muggia
Apr 3, 2020·Angiologii︠a︡ i sosudistai︠a︡ khirurgii︠a︡ = Angiology and vascular surgery·V V ShlominI V Tigrov
Sep 1, 1994·European Journal of Vascular Surgery·A GordonP Morris