PMID: 11914120Mar 27, 2002Paper

Differential effects of glucose and fructose on hexose metabolism in dog spermatozoa

Reproduction : the Official Journal of the Society for the Study of Fertility
T RigauJ E Rodríguez-Gil

Abstract

Incubation of dog spermatozoa with 10 mmol l(-1) glucose or fructose rapidly increased the intracellular content of glucose 6-phosphate and fructose 6-phosphate, although the effect of fructose was greater. These effects were correlated with increases in ATP, ribose 5-phosphate and glycogen contents, and in the rates of formation of L-lactate and CO2. In all cases, except for ATP and glycogen, the effect of fructose was greater than that of glucose. The total hexokinase activity of the crude extracts of dog spermatozoa was more sensitive to fructose than to glucose at lower concentrations (0.1-3.0 mmol l(-1)). Both monosaccharides induced a fast and intense increase in the overall tyrosine phosphorylation of dog spermatozoa, although their specific induced-phosphorylation patterns differed slightly. Glut 3 and Glut 5 hexose transporters were the main hexose transporters in dog spermatozoa; however, other possible SGLT family-related hexose transporters were also localized. These data indicate that, at concentrations from 1 mmol l(-1) to 10 mmol l(-1), fructose has a stronger effect than glucose on hexose metabolism of dog spermatozoa. These differences appear to be related to variations in the sensitivity of hexokinase activity...Continue Reading

Citations

Aug 17, 2014·Molecular and Cellular Endocrinology·Tânia R DiasPedro F Oliveira
Apr 10, 2008·American Journal of Physiology. Endocrinology and Metabolism·Veronique Douard, Ronaldo P Ferraris
Mar 24, 2011·Reproduction, Fertility, and Development·J M Fernández-NovellJ E Rodríguez-Gil
Nov 19, 2003·FEBS Letters·Silvia MarinMarta Cascante
Jul 15, 2004·FEBS Letters·Josep M Fernández-NovellJoan E Rodríguez-Gil
Jan 28, 2003·Molecular Reproduction and Development·Maria J PalomoJoan E Rodríguez-Gil
Feb 26, 2013·Animal Reproduction Science·Yongsheng TianSonglin Chen
Mar 17, 2010·Animal Reproduction Science·Marc YesteSergi Bonet
Dec 20, 2005·Molecular Reproduction and Development·Antonio MedranoJoan E Rodríguez-Gil
Sep 17, 2013·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Vikas Kumar Roy, Amitabh Krishna
Nov 26, 2009·Reproduction in Domestic Animals = Zuchthygiene·D BucciG Galeati
Dec 6, 2008·Reproduction in Domestic Animals = Zuchthygiene·D BucciG Galeati
Sep 29, 2004·Theriogenology·Suppawiwat PonglowhapanCatharina Linde Forsberg
Jun 22, 2015·Theriogenology·Joan E Rodríguez-Gil, Sergi Bonet
May 28, 2013·Biochimica Et Biophysica Acta·K Göran RonquistAnders Larsson
Jul 28, 2016·PloS One·Jason R HerrickRebecca L Krisher
Jul 28, 2012·Biology of Reproduction·Summer G GoodsonDeborah A O'Brien
Apr 29, 2016·PLoS Computational Biology·Carles FoguetMarta Cascante

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