PMID: 3770207Nov 10, 1986Paper

Differential effects of noradrenaline and glucagon on lipolysis and fatty-acid utilization in brown adipose tissue

FEBS Letters
R J Howland, A D Benning

Abstract

The relative effects of noradrenaline (300 pM-3 microM) and glucagon (30 pM-300 nM) upon lipolysis and fatty acid utilization rates in brown adipose tissue from warm- (WA) and cold-acclimated (CA) rats, were: lipolytic sensitivity and responsiveness to the agonists were reduced in CA tissue; in CA tissue, at 300 pM, glucagon promoted fatty acid utilization more than noradrenaline; glucagon at 300 pM increased fatty acid utilization in WA tissue. The data suggest that glucagon has a physiological role in brown adipose tissue, modulating events subsequent to NA- and glucagon-induced lipolysis, promoting fatty acid utilization.

References

Sep 6, 1979·Nature·N J Rothwell, M J Stock
Aug 1, 1979·Pflügers Archiv : European journal of physiology·A KuroshimaT Yahata
Dec 1, 1977·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·T RabiA Gutman
Oct 1, 1974·The American Journal of Physiology·J A Williams, E K Matthews
Feb 1, 1970·The Journal of Physiology·M J Hardman, D Hull
Jan 1, 1984·Comparative Biochemistry and Physiology. A, Comparative Physiology·M L PuertaA Fraile
Jan 1, 1982·International Review of Cytology·J Nedergaard, O Lindberg
May 1, 1982·The Journal of Clinical Investigation·J B YoungL Landsberg
Jun 8, 1981·Life Sciences·T YahataA Kuroshima
Jan 1, 1981·The Japanese Journal of Physiology·A KuroshimaT Ohno

❮ Previous
Next ❯

Citations

Oct 29, 1998·The American Journal of Physiology·A DickerJ Nedergaard
Dec 24, 1998·Molecular and Cellular Endocrinology·A MoralesH Barré

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.