Differential interhemispheric cooling and ICP compartmentalization in a patient with left ICA occlusion

Acta neurochirurgica
Huan WangW Olivero

Abstract

We report a case of a 69-year-old white female who presented with a large left internal carotid artery occlusive stroke from a cardiogenic embolus. She was enrolled in an institutional study using a specially designed cooling helmet. Bilateral intracranial pressure (ICP) and temperature probes were placed to determine if there was any differential cooling and ICP compartmentalization between the two hemispheres. We demonstrated a significant temperature gradient between the infarcted and the non-infarcted hemisphere. A significant inter-hemispheric ICP gradient was also observed. We believe that this is the first demonstration of preferential cooling of the infarcted hemisphere over the non-infarcted hemisphere with regional surface hypothermia.

References

Nov 1, 1992·Neurosurgery·G GambardellaF Tomasello
Jan 1, 1997·Neuroscience and Biobehavioral Reviews·F C BaroneR F White
Jan 5, 2002·Journal of Neurosurgery·C G MarkgrafM R Moody
Dec 31, 2002·Surgical Neurology·Anthony L D'AmbrosioE Sander Connolly
Apr 17, 2004·Journal of Neurosurgery·Huan WangDavid Wang

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Citations

Mar 1, 2013·Therapeutic Hypothermia and Temperature Management·Edited By Mary Kay Bader
Jan 27, 2009·Journal of Neuroscience Methods·Emanuela KellerJuerg Fröhlich
Jan 14, 2015·Translational Neuroscience·Huan WangBrad Sutton
Nov 7, 2019·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Thomas Mindermann

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