Differential morphology of the superior olivary complex of Meriones unguiculatus and Monodelphis domestica revealed by calcium-binding proteins

Brain Structure & Function
I Bazwinsky-WutschkeRudolf Rübsamen

Abstract

In mammals, the superior olivary complex (SOC) of the brainstem is composed of nuclei that integrate afferent auditory originating from both ears. Here, the expression of different calcium-binding proteins in subnuclei of the SOC was studied in distantly related mammals, the Mongolian gerbil (Meriones unguiculatus) and the gray short-tailed opossum (Monodelphis domestica) to get a better understanding of the basal nuclear organization of the SOC. Combined immunofluorescence labeling of the calcium-binding proteins (CaBPs) parvalbumin, calbindin-D28k, and calretinin as well as pan-neuronal markers displayed characteristic distribution patterns highlighting details of neuronal architecture of SOC nuclei. Parvalbumin was found in almost all neurons of SOC nuclei in both species, while calbindin and calretinin were restricted to specific cell types and axonal terminal fields. In both species, calbindin displayed a ubiquitous and mostly selective distribution in neurons of the medial nucleus of trapezoid body (MNTB) including their terminal axonal fields in different SOC targets. In Meriones, calretinin and calbindin showed non-overlapping expression patterns in neuron somata and terminal fields throughout the SOC. In Monodelphis, c...Continue Reading

References

Aug 1, 1992·Trends in Neurosciences·K G BaimbridgeJ H Rogers
Jun 8, 1992·The Journal of Comparative Neurology·P E KelleyJ P Walton
Aug 15, 1991·The Journal of Comparative Neurology·K K GlendenningR J Wenthold
Nov 1, 1991·The Journal of Comparative Neurology·M L ZettelW E O'Neill
Dec 22, 1991·The Journal of Comparative Neurology·N KuwabaraJ M Zook
Mar 1, 1991·Journal of Neurophysiology·P G Finlayson, D M Caspary
Dec 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·L WinskyD M Jacobowitz
Jan 15, 1989·The Journal of Comparative Neurology·D H SanesE W Rubel
Jan 1, 1987·Annual Review of Neuroscience·P J Marangos, D E Schmechel
Jan 1, 1986·Brain, Behavior and Evolution·C E Carr
May 1, 1987·The American Journal of Anatomy·R H Helfert, I R Schwartz
May 22, 1986·The Journal of Comparative Neurology·N B Cant, J H Casseday
Feb 8, 1985·The Journal of Comparative Neurology·K K GlendenningR B Masterton
Aug 15, 1985·The Journal of Comparative Neurology·K M SpanglerC K Henkel
Nov 4, 1968·Zeitschrift Für Anatomie Und Entwicklungsgeschichte·D K Morest
Aug 1, 1969·The Journal of Comparative Neurology·K K Osen
Sep 1, 1980·Stain Technology·F GallyasL Záborszky
Jul 20, 1984·The Journal of Comparative Neurology·N B Cant
Nov 14, 1983·Brain Research·R J ThompsonJ Rode
Apr 20, 1981·The Journal of Comparative Neurology·K K GlendenningR B Masterton
Mar 13, 1995·The Journal of Comparative Neurology·J KilL M Kitzes
Jun 1, 1994·Hearing Research·S B Frost, R B Masterton
Feb 1, 1993·Cell and Tissue Research·C AndressenM R Celio
Nov 1, 1995·Audiology : Official Organ of the International Society of Audiology·K Reimer

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Citations

Jun 22, 2017·Hearing Research·Tatiana FechRandy J Kulesza

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