Differential neuronal plasticity in mouse hippocampus associated with various periods of enriched environment during postnatal development

Brain Structure & Function
Salma HosseinyAlice Guyon

Abstract

Enriched environment (EE) is characterized by improved conditions for enhanced exploration, cognitive activity, social interaction and physical exercise. It has been shown that EE positively regulates the remodeling of neural circuits, memory consolidation, long-term changes in synaptic strength and neurogenesis. However, the fine mechanisms by which environment shapes the brain at different postnatal developmental stages and the duration required to induce such changes are still a matter of debate. In EE, large groups of mice were housed in bigger cages and were given toys, nesting materials and other equipment that promote physical activity to provide a stimulating environment. Weaned mice were housed in EE for 4, 6 or 8 weeks and compared with matched control mice that were raised in a standard environment. To investigate the differential effects of EE on immature and mature brains, we also housed young adult mice (8 weeks old) for 4 weeks in EE. We studied the influence of onset and duration of EE housing on the structure and function of hippocampal neurons. We found that: (1) EE enhances neurogenesis in juvenile, but not young adult mice; (2) EE increases the number of synaptic contacts at every stage; (3) long-term potent...Continue Reading

References

Apr 1, 1970·The American Journal of Anatomy·A Peters, I R Kaiserman-Abramof
Dec 20, 1994·Proceedings of the National Academy of Sciences of the United States of America·M B MoserP Andersen
Jan 7, 1993·Nature·T V Bliss, G L Collingridge
Oct 1, 1996·The Journal of Neuropsychiatry and Clinical Neurosciences·E L BennettM R Rosenzweig
May 30, 1998·Journal of Neurophysiology·A Y HsiaR A Nicoll
Apr 5, 2001·Journal of Neurophysiology·T C Foster, T C Dumas
Nov 16, 2002·Progress in Brain Research·Thomas C Foster
Jul 16, 2003·The European Journal of Neuroscience·J L Bizon, M Gallagher
Mar 23, 2004·The Journal of Physiology·Leon L Voronin, Enrico Cherubini
May 21, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Laura CanceddaLamberto Maffei
Nov 29, 2005·Frontiers in Neuroendocrinology·Cheryl L Sisk, Julia L Zehr
Dec 20, 2005·Current Opinion in Neurobiology·Tomoko Tada, Morgan Sheng
Jun 30, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael C AshbyJeremy M Henley
Aug 15, 2006·Nature Neuroscience·Catherine HeurteauxMichel Lazdunski
Aug 23, 2006·Nature Reviews. Neuroscience·Jess Nithianantharajah, Anthony J Hannan
Feb 14, 2008·Nature Reviews. Neuroscience·Nelson Spruston
Feb 3, 2009·Neuron·Karen ZitoKarel Svoboda
Mar 10, 2009·Trends in Neurosciences·Alessandro SaleLamberto Maffei
Mar 10, 2009·The Journal of Biological Chemistry·Frédéric JaskolskiJeremy M Henley
Dec 19, 2009·Cell Death and Differentiation·L BaroncelliL Maffei
Feb 9, 2010·Trends in Neurosciences·Haruo KasaiJun Noguchi
Apr 16, 2010·Journal of Neurophysiology·Michael J EckertWickliffe C Abraham
Apr 22, 2010·Frontiers in Cellular Neuroscience·Alessandro SaleLamberto Maffei
May 31, 2011·Neurobiology of Aging·Stanley E Lazic
Jun 7, 2011·Current Topics in Behavioral Neurosciences·Rosa Redolat, Patricia Mesa-Gresa
Apr 12, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nannan GuoNoriko Osumi
Aug 6, 2013·Neuropharmacology·Benjamin SiddowayHouhui Xia
Apr 1, 2014·Cell·Eric R KandelMark R Mayford

❮ Previous
Next ❯

Citations

Jun 11, 2016·Biochemical and Biophysical Research Communications·Yuki TomigaYasuki Higaki
Oct 11, 2016·Behavioral and Brain Functions : BBF·Daniel Guerreiro DinizCristovam Wanderley Picanço Diniz
May 28, 2017·Behavioural Brain Research·V StamenkovicP Andjus
Jun 24, 2019·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Emma C PerezJ Leigh Leasure
Jul 2, 2020·Journal of Materials Science. Materials in Medicine·Stephanie Sánchez-TorresHermelinda Salgado-Ceballos
Dec 21, 2019·Scientific Reports·Teresa Morera-HerrerasLaurent Venance
Jun 29, 2018·Frontiers in Synaptic Neuroscience·Hadi ZarifAgnès Petit-Paitel
Mar 14, 2020·Brain, Behavior, and Immunity·Chiomah EzeomahIrma E Cisneros
May 29, 2021·Neuropharmacology·Daniel D Cooper, Bruno G Frenguelli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.