PMID: 9539791May 16, 1998Paper

Differential patterns of acquired virulence genes distinguish Salmonella strains

Proceedings of the National Academy of Sciences of the United States of America
C P ConnerM J Mahan

Abstract

Analysis of several Salmonella typhimurium in vivo-induced genes located in regions of atypical base composition has uncovered acquired genetic elements that cumulatively engender pathogenicity. Many of these regions are associated with mobile elements, encode predicted adhesin and invasin-like functions, and are required for full virulence. Some of these regions distinguish broad host range from host-adapted Salmonella serovars and may contribute to inherent differences in host specificity, tissue tropism, and disease manifestation. Maintenance of this archipelago of acquired sequence by selection in specific hosts reveals a fossil record of the evolution of pathogenic species.

References

Mar 1, 1992·Journal of Bacteriology·N R Benson, B S Goldman
Apr 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·U H StroeherP A Manning
May 1, 1990·Journal of General Microbiology·R M Jeter
Jan 1, 1972·Molecular & General Genetics : MGG·H Schmieger
Jan 31, 1995·Proceedings of the National Academy of Sciences of the United States of America·M J MahanJ J Mekalanos
Feb 14, 1995·Proceedings of the National Academy of Sciences of the United States of America·S L Liu, K E Sanderson
Feb 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·E A GroismanH Ochman
Mar 1, 1993·Journal of Bacteriology·K Maneewannakul, K Ippen-Ihler
Jun 1, 1996·Infection and Immunity·J M FleckensteinE A Elsinghorst
Mar 1, 1996·Infection·H M HasselhornF W Tiller
Oct 1, 1996·Proceedings of the National Academy of Sciences of the United States of America·P K Brown, R Curtiss
Nov 1, 1996·Genetics·A MochizukiY Iwasa
Dec 1, 1996·Infection and Immunity·H Ochman, E A Groisman
Dec 1, 1996·FEMS Microbiology Letters·S J BillingtonJ I Rood
Feb 4, 1997·Proceedings of the National Academy of Sciences of the United States of America·D M HeithoffM J Mahan
Apr 1, 1997·Journal of Bacteriology·U H StroeherP A Manning
Sep 5, 1997·Science·F R BlattnerY Shao
Feb 3, 1998·Trends in Microbiology·D M HeithoffM J Mahan

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Citations

Oct 12, 2000·Current Opinion in Biotechnology·P B Rainey, G M Preston
Mar 9, 2000·Trends in Microbiology·F de la Cruz, J Davies
Apr 1, 2000·Microbes and Infection·S L MarcusB B Finlay
Feb 12, 2009·Journal of Proteome Research·Saiful M ChowdhuryRichard D Smith
Mar 18, 2008·Nature Reviews. Microbiology·Stephen Bentley
Feb 24, 2001·Environmental Microbiology·P B Rainey
Mar 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·Chenguang FanThomas A Bobik
Aug 29, 2012·Proceedings of the National Academy of Sciences of the United States of America·Chenguang FanThomas A Bobik
Mar 5, 2005·The Journal of Infectious Diseases·Johanna P DailyDyann F Wirth
Sep 22, 2007·Foodborne Pathogens and Disease·Steven L FoleyRobert D Walker
Dec 3, 1999·Immunological Reviews·J C SirardJ P Kraehenbuhl
Oct 5, 2010·Applied and Environmental Microbiology·Donna E DavidSteven L Foley
Nov 3, 2010·Applied and Environmental Microbiology·Shabarinath Srikumar, Thilo M Fuchs
Feb 5, 2008·Applied and Environmental Microbiology·Douglas M HeithoffMichael J Mahan
Mar 23, 2011·Applied and Environmental Microbiology·Rebecca Munk VejborgPer Klemm
Jul 4, 2003·Applied and Environmental Microbiology·Mollie D Winfield, Eduardo A Groisman
Mar 18, 2008·Journal of Bacteriology·Tatiana E ErovaAshok K Chopra
Feb 6, 2007·Journal of Bacteriology·Ping XuGregory A Buck
Feb 29, 2000·Journal of Bacteriology·S M JulioM J Mahan
May 1, 2002·Journal of Clinical Microbiology·Mamuka KotetishviliAlexander Sulakvelidze
Mar 23, 2011·BMC Microbiology·Matthew R EvansHosni M Hassan
Sep 10, 2008·BMC Microbiology·Matthew A Lambert, Stephen G J Smith
Mar 30, 2011·PloS One·Nat F BrownB Brett Finlay

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