Differential patterns of opioid use: defining persistent opioid use in a prescription database

European Journal of Pain : EJP
K SvendsenO Fredheim

Abstract

The aim of this study was to develop definitions to identify persons with clinically different patterns of persistent opioid use based on data from prescription databases. The study is based on data from the Norwegian Prescription Database using all dispensed opioid prescriptions during 2005-2008. Three definitions of persistent opioid use were developed using the following patient criteria: different levels of dispensed opioid amounts, number of prescriptions and the number of quarters out of the year in which prescriptions were dispensed. The three definitions each have some typical patient characteristics attached to them. The strict definition describes a typical patient using opioids to achieve a continuous serum concentration in the therapeutic range, the intermediate definition represents a typical patient using opioids daily but not around the clock and the wide definition describes a typical patient who uses opioids most of the days. To study whether the definitions accurately represent long-term use, the patient population was followed for 3 years, and the retention rate within each definition was measured. The point prevalence of persistent opioid use in Norway (4,681,134 inhabitants) as defined by the strict, interm...Continue Reading

References

May 23, 2001·Journal of Pain and Symptom Management·R AndersonC Schlicht
Aug 26, 2003·European Journal of Pain : EJP·Eija KalsoMichael Zenz
Nov 9, 2004·European Journal of Pain : EJP·Tone RustøenChristine Miaskowski
Apr 29, 2005·Journal of Pain and Symptom Management·Lene JarlbaekJakob Kragstrup
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
Mar 4, 2006·Pharmacoepidemiology and Drug Safety·Susan E AndradeK Arnold Chan
Feb 15, 2007·The Annals of Pharmacotherapy·Asad E PatanwalaBrian L Erstad
Feb 4, 2009·The Journal of Pain : Official Journal of the American Pain Society·Roger ChouUNKNOWN American Pain Society-American Academy of Pain Medicine Opioids Guidelines Panel
Jun 10, 2009·European Journal of Pain : EJP·Olav Magnus S FredheimPetter C Borchgrevink
Sep 1, 2009·Pharmacoepidemiology and Drug Safety·Denise BoudreauConstance Weisner
Dec 8, 2009·Basic & Clinical Pharmacology & Toxicology·Kari FuruHenrik Toft Sørensen

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Citations

Jan 23, 2013·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Line PedersenOlav Magnus S Fredheim
Sep 4, 2015·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Nabarun DasguptaSteve Marshall
Aug 6, 2015·Acta Anaesthesiologica Scandinavica·A MellbyeO M S Fredheim
Sep 6, 2012·Acta Anaesthesiologica Scandinavica·A MellbyeO M S Fredheim
Jan 21, 2014·European Journal of Pain : EJP·A MellbyeO M S Fredheim
Mar 7, 2014·Acta Anaesthesiologica Scandinavica·Kristian SvendsenSvetlana Skurtveit
Feb 17, 2018·British Journal of Clinical Pharmacology·Samanta LalicJenni Ilomäki
Mar 13, 2018·Critical Care Medicine·Troels MunchHenrik Toft Sørensen
Dec 19, 2019·Pharmacoepidemiology and Drug Safety·Ruchir N KarmaliAndrew W Roberts
Jun 27, 2015·Acta Anaesthesiologica Scandinavica·A B HansenO M Fredheim
Oct 9, 2020·The Journal of Pain : Official Journal of the American Pain Society·Yun ShenAmie J Goodin
Feb 26, 2021·British Journal of Clinical Pharmacology·Juliana de Oliveira CostaSallie-Anne Pearson

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