Differential response of operant self-injury to pharmacologic versus behavioral treatment

Journal of Developmental and Behavioral Pediatrics : JDBP
F C MaceJ E Mauk

Abstract

The purpose of this study was to investigate the hypothesis that self-injurious behavior (SIB) maintained by environmental factors will be more effectively treated by behavioral treatments than by haloperidol. Fifteen subjects were enrolled in this study. The efficacy of both haloperidol and a behavioral treatment was assessed. At the onset of treatment, subjects were randomized to receive either haloperidol or a placebo. During each day of treatment, data were collected during sessions with a behavioral treatment and sessions without a behavioral treatment. Behavioral treatment resulted in a statistically significant decrease in SIB, but haloperidol did not. Eighty-three percent of subjects were classified as responders to the behavioral treatment whereas only 25% of the subjects were responders to haloperidol (p = .019). We conclude that individuals with operant SIB are more likely to respond to behavioral treatments than to haloperidol.

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Citations

Mar 10, 2009·Dental Clinics of North America·Maureen Romer, Nancy J Dougherty
Sep 24, 2015·Journal of Applied Behavior Analysis·Alison D Cox, Javier Virues-Ortega
Aug 1, 2015·Journal of Applied Behavior Analysis·Louis P HagopianJennifer R Zarcone
Jan 7, 2003·Child and Adolescent Psychiatric Clinics of North America·Kenneth E Towbin
Jul 22, 2004·The Cochrane Database of Systematic Reviews·J Brylewski, L Duggan
Dec 27, 2005·Human Psychopharmacology·Giampaolo La MalfaAlessandro Castellani
Mar 25, 2008·Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie·Johannes Rojahn, Pia Bienstein
Dec 17, 2010·Expert Review of Neurotherapeutics·Hazem Shoirah, Hesham M Hamoda

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