PMID: 8580740Oct 1, 1995Paper

Differential time courses of c-fos mRNA expression in hippocampal subfields following acquisition and recall testing in mice

Brain Research. Cognitive Brain Research
V Bertaina, C Destrade

Abstract

Spatio-temporal patterns of c-fos mRNA expression were studied in the mouse brain following the partial acquisition of an appetitive conditioning task in a Skinner box. We used two experimental situations: during the initial acquisition of the task (acquisition paradigm) and during the retention test (recall paradigm). In both paradigms the in situ hybridization signal was exclusively located in the hippocampal formation and the posterior cingulate cortex. However, the time-dependent pattern of expression was quite different according to the experimental situation: mRNA levels peaked at 90 min post-test in both paradigms but returned to basal (control) level by 180 min in the acquisition group, while in CA3 and DG subfields, high levels of mRNA expression were maintained at 180 min in the recall group. Taken together these results suggest that the IEG c-fos is implicated in the different phases of post-acquisition memory processes and involve a differential spatio-temporal regulation of its expression in hippocampal subfields.

References

Jan 1, 1991·Molecular Neurobiology·W C AbrahamW P Tate
Sep 1, 1990·Behavioral and Neural Biology·W TischmeyerH Matthies
Jan 1, 1987·Journal of Mathematical Biology·I Nebenzahl
Nov 1, 1984·Psychological Bulletin·H P Davis, L R Squire
Mar 1, 1984·Experimental Neurology·D M FinchT L Babb
Sep 1, 1980·Brain : a Journal of Neurology·C Baleydier, F Mauguiere
Feb 11, 1982·Brain Research·M GauthierB Soumireu-Mourat
Dec 20, 1993·Behavioural Brain Research·I IzquierdoN Paczko
Jan 7, 1993·Nature·T V Bliss, G L Collingridge
Apr 1, 1993·Brain Research. Molecular Brain Research·C HeurteauxM Lazdunski
Mar 1, 1993·Brain Research. Molecular Brain Research·J DemmerW P Tate
Jan 1, 1991·The European Journal of Neuroscience·Konstantin V. Anokhin, Steven P. R. Rose
May 12, 2006·International Journal of Cancer. Journal International Du Cancer·H M LiS W Tsao

❮ Previous
Next ❯

Citations

Aug 25, 2004·Neurotoxicity Research·Lionel Muller IgazJorge H Medina
Jun 1, 1997·Brain Research. Molecular Brain Research·A P Da CostaK M Kendrick
Oct 6, 1998·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·S Davis, S Laroche
Sep 2, 1997·Proceedings of the National Academy of Sciences of the United States of America·S CavallaroD L Alkon
Oct 18, 2015·Clinical and Experimental Pharmacology & Physiology·Henrique P SantiagoCândido C Coimbra
Nov 15, 2011·Neuroscience and Biobehavioral Reviews·Michael A van der Kooij, Carmen Sandi
Nov 19, 2004·Brain Research. Molecular Brain Research·Lionel Müller IgazJorge H Medina
Jul 3, 2010·Behavioral and Brain Functions : BBF·Lisa A FeldmanJosephine Nalbantoglu
Dec 15, 2007·Nature Protocols·Nohjin KeePaul W Frankland
Jun 8, 2021·Experimental Brain Research·Mehar NaseemSuhel Parvez

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.