Differentially expressed microRNAs in biochemically characterized FrieswalTM crossbred bull semen.

Animal Biotechnology
Rani SinghN V Patil

Abstract

In addition to the transmission of paternal genome, spermatozoa also carry coding as well as noncoding microRNAs (miRNAs) into the female oocyte during the process of biological fertilization. Based on RNA deep sequencing, a total 28 number of differentially expressed miRNAs were cataloged in categorized FrieswalTM crossbred (Holstein Friesian X Sahiwal) bull semen on the basis of conception rate (CR) in field progeny testing program. Validation of selected miRNAs viz. bta-mir-182, bta-let-7b, bta-mir-34c and bta-mir-20a revealed that, superior bull semen having comparatively (p < .05) lower level of all the miRNAs in contrast to inferior bull semen. Additionally, it was illustrated that, bta-mir-20a and bta-mir-34c miRNAs are negatively (p < .01) correlated with seminal plasma catalase (CAT) activity and glutathione peroxidase (GPx) level. Interactome studies identified that bta-mir-140, bta-mir-342, bta-mir-1306 and bta-mir-217 can target few of the important solute carrier (SLC) proteins viz. SLC30A3, SLC39A9, SLC31A1 and SLC38A2, respectively. Interestingly, it was noticed that all the SLCs were significantly (p < .05) expressed at higher level in superior quality bull semen and they are negatively correlated (p < .01) with...Continue Reading

References

Jan 1, 1995·Journal of Reproduction and Fertility·J F GriveauD Le Lannou
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
Jan 30, 2003·Journal of Endocrinological Investigation·A GiannattasioG Lombardi
May 14, 2004·Nature·G Charles OstermeierStephen A Krawetz
Oct 27, 2004·The Veterinary Journal·T J Parkinson
Jun 7, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Heidar TavilaniHojatollah Saeidi
Mar 7, 2007·The Journal of Veterinary Medical Science·Eiichi KawakamiToshihiko Tsutsui
May 8, 2007·Theriogenology·P J Chenoweth
Jun 23, 2007·Theriogenology·A BoerkeB M Gadella
Jul 21, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·Sheena E M Lewis
Jan 8, 2008·Molecular and Cellular Endocrinology·Tal Almog, Zvi Naor
Apr 15, 2008·FEBS Letters·Fang SunXiaofei Zheng
Aug 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Munekazu YamakuchiCharles J Lowenstein
Mar 24, 2009·Trends in Molecular Medicine·Michelle W M LiC Yan Cheng
Apr 11, 2009·Proceedings of the National Academy of Sciences of the United States of America·Hun-Way HwangJoshua T Mendell
Aug 22, 2009·Cell Death and Differentiation·N R ChristoffersenA H Lund
Nov 29, 2011·Methods in Cell Biology·Priscilla M Van WynsbergheAmy E Pasquinelli
Dec 29, 2011·Proceedings of the National Academy of Sciences of the United States of America·Wei-Min LiuWilliam S B Yeung
Sep 18, 2012·Reproductive Biology and Endocrinology : RB&E·Aruna GovindarajuErdogan Memili
Jan 19, 2013·Reproduction, Fertility, and Development·Mohammad Bozlur RahmanAnn Van Soom
Jul 17, 2013·Human Reproduction Update·Meritxell JodarUNKNOWN Reproductive Medicine Network
May 6, 2014·Frontiers in Genetics·Neha Nagpal, Ritu Kulshreshtha
Jun 3, 2014·Fertility and Sterility·Noora Kotaja
Sep 3, 2014·Reproductive Biology and Endocrinology : RB&E·Allison TschernerJonathan LaMarre
May 23, 2015·Reproduction in Domestic Animals = Zuchthygiene·M FagerlindK Klinga-Levan
Apr 30, 2017·RNA·Shivani SharmaRitu Kulshreshtha
Dec 24, 2017·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Francesca MancusoLorella Marinucci
Feb 9, 2018·Reproduction in Domestic Animals = Zuchthygiene·R SinghA Kumar

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