Differentiating (131)I Radiation Sialadenitis From Autoimmune (Sjögren Syndrome) Sialadenitis: Case Report

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
L Mandel, Loren Wissner Greene

Abstract

Radioactive iodine ((131)I) is used effectively for the treatment of differentiated thyroid cancers. Because it is actively secreted by the salivary glands, radiation damage to these glands can occur. Obstructive swellings after mealtime salivary stimulation are common occurrences. Dry mouth is not usually seen if low doses of (131)I are used. A subjective complaint of xerostomia in a patient treated with (131)I 75.8 mCi proved to be related to the simultaneous presence of Sjögren syndrome (SS). Serologic, histologic, scintigraphic, and salivary volume findings and the patient's subjective complaints served to establish the pre-existence of SS.

Citations

Nov 18, 2020·The Laryngoscope·Ryan K ThorpeHenry T Hoffman
Jul 9, 2021·The Laryngoscope·Samanta BuchholzerFrancis Marchal

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