Differentiating benign and malignant salivary gland tumours: diagnostic criteria and the accuracy of dynamic contrast-enhanced MRI with high temporal resolution

The British Journal of Radiology
P D LamT Kurabayashi

Abstract

To determine the optimal diagnostic criterion of dynamic contrast-enhanced MRI (DCE-MRI) for predicting salivary gland malignancy using a dynamic sequence with high temporal resolution, as well as the accuracy of this technique. The DCE-MRI findings of 98 salivary gland tumours (74 benign and 24 malignant) were reviewed. MR images were sequentially obtained at 5-s intervals for 370 s. Two parameters, peak time and washout ratio (WR) were determined from the time-signal intensity curve. The optimal thresholds of these parameters for differentiating benign and malignant tumours were determined, along with the diagnostic accuracy of the criterion using these thresholds. A peak time of 150 s and a WR of 30% were identified as optimal thresholds. As the criterion for malignancy, the combination of peak time <150 s and WR <30% provided a sensitivity of 79% (19/24), specificity of 95% (70/74) and an overall accuracy of 91% (89/98). Three of the five false-negative cases were malignant lymphomas of the parotid gland. Peak time <150 s with WR <30% comprised the optimal diagnostic criterion in predicting salivary gland malignancy, providing a sensitivity of 79% and specificity of 95%. The use of high temporal resolution might improve the...Continue Reading

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Citations

Apr 7, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Takenori OgawaYukio Katori
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May 26, 2017·PloS One·Marcelo Aldrighi MoreiraPriscyla Waleska Simões
Nov 30, 2018·Oral Radiology·Ahmed Abdel Khalek Abdel Razek
Oct 18, 2020·Odontology·Tohru KurabayashiShin Nakamura
Sep 19, 2020·Diagnostic and Interventional Imaging·H CoudertP-F Montoriol
Apr 27, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jessica L GeigerPatrick Ha
Apr 19, 2021·European Journal of Radiology·Davide MaraghelliStefano Colagrande
Sep 25, 2021·Dento Maxillo Facial Radiology·Fabian Henry Jürgen ElsholtzLars-Arne Schaafs

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