Differentiating cognitive or motor dimensions associated with the perception of fall-related self-efficacy in Parkinson's disease

NPJ Parkinson's Disease
Taylor ChomiakBin Hu

Abstract

In Parkinson's disease (PD), concurrent declines in cognitive and motor domain function can severely limit an individual's ability to conduct daily tasks. Current diagnostic methods, however, lack precision in differentiating domain-specific contributions of cognitive or motor impairments based on a patients' clinical manifestation. Fear of falling (FOF) is a common clinical manifestation among the elderly, in which both cognitive and motor impairments can lead to significant barriers to a patients' physical and social activities. The present study evaluated whether a set of analytical and machine-learning approaches could be used to help delineate boundary conditions and separate cognitive and motor contributions to a patient's own perception of self-efficacy and FOF. Cognitive and motor clinical scores, in conjunction with FOF, were collected from 57 Parkinson's patients during a multi-center rehabilitation intervention trial. Statistical methodology was used to extract a subset of uncorrelated cognitive and motor components associated with cognitive and motor predictors, which were then used to independently identify and visualize cognitive and motor dimensions associated with FOF. We found that a central cognitive process, ...Continue Reading

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Methods Mentioned

BETA
PCA

Clinical Trials Mentioned

ISRCTN06023392

Software Mentioned

iOS
Ambulosono
GaitReminder
SVM
iOS GaitReminder App
R

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