Differentiating malignant and benign lymph nodes using endobronchial ultrasound elastography

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Ching-Kai LinChao-Chi Ho

Abstract

Endobronchial ultrasound (EBUS) elastography is a new technique that provides information on tissue compressibility during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). The purposes of this study were to evaluate the utility of EBUS elastography in differentiating malignant and benign mediastinal lymph nodes (LNs) and to explore the factors that influence its accuracy. A retrospective chart review of patients who underwent EBUS-TBNA from October 2016 to July 2017 was performed. EBUS with conventional B-mode features and elastographic patterns were compared with the final pathology results or clinical follow-up. We used the following EBUS elastographic patterns for classification: type 1, predominantly non-blue (green, yellow and red); type 2, part blue, part non-blue; type 3, predominantly blue. The potential impacts of the characteristics of LNs, the underlying lung diseases and obtaining fibrotic components from EBUS-TBNA specimens were evaluated relative to the accuracy of EBUS elastography. A total of 206 LNs from 94 patients were retrospectively evaluated. In classifying type 1 as 'benign' and type 3 as 'malignant,' the sensitivity, specificity, positive predictive value, negative predictive...Continue Reading

Citations

Feb 9, 2020·The Clinical Respiratory Journal·Atefeh AbediniArda Kiani
Jul 29, 2020·Endoscopic Ultrasound·Xinxin ZhiFelix J F Herth
Sep 4, 2020·European Respiratory Review : an Official Journal of the European Respiratory Society·Sharad Chandrika, Lonny Yarmus
Jun 17, 2021·Journal of Bronchology & Interventional Pulmonology·Karan MadanRandeep Guleria

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