Differentiating Mass-Forming Autoimmune Pancreatitis From Pancreatic Ductal Adenocarcinoma on the Basis of Contrast-Enhanced MRI and DWI Findings

AJR. American Journal of Roentgenology
Seo-Youn ChoiYoon-Hyeong Choi

Abstract

The purpose of this study was to assess value of contrast-enhanced MRI, MRCP, and DWI for differentiating mass-forming autoimmune pancreatitis (AIP) from pancreatic ductal adenocarcinoma (PDAC). This study included 15 patients with mass-forming AIP and 79 with PDAC who underwent gadoxetic acid-enhanced MRI with DWI and MRCP. Two radiologists evaluated the MRI findings in consensus. Statistically significant imaging findings were identified through univariate and multivariate analyses, and their diagnostic performance for predicting mass-forming AIP was analyzed. In the univariate analysis, multiplicity, similar or high signal intensity on portal phase and 3- and 20-minute delayed phase images, homogeneous enhancement, no peripancreatic fat infiltration, no internal cystic or necrotic portion, capsulelike rim, no upstream pancreatitis, no vascular invasion, and duct penetrating sign were more frequently observed (p < 0.05) in mass-forming AIP. The apparent diffusion coefficient (ADC) value was also significantly lower for mass-forming AIP than for PDAC (0.96 ± 0.14 versus 1.13 ± 0.23 × 10(-3) mm(2)/s; p < 0.001). The optimal cutoff value of ADC for differentiating mass-forming AIP from PDAC was 0.9407 × 10(-3) mm(2)/s. In multiv...Continue Reading

References

May 9, 1998·AJR. American Journal of Roentgenology·H IrieK Masuda
Mar 16, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Dhiraj YadavSuresh T Chari
Jul 18, 2006·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Suresh T ChariMichael B Farnell
Aug 26, 2006·Journal of Gastroenterology·Kazuichi OkazakiUNKNOWN Research Committee of Intractable Diseases of the Pancreas
Jan 24, 2007·AJR. American Journal of Roentgenology·Tomoaki IchikawaHideki Fujii
Jan 24, 2008·AJR. American Journal of Roentgenology·Naoki TakahashiSuresh T Chari
Jul 5, 2008·Journal of Gastroenterology·Makoto OtsukiUNKNOWN Research Committee of Intractable Pancreatic Diseases provided by the Ministry of Health, Labour and Welfare of Japan and th
Apr 21, 2009·Journal of Gastroenterology·Tooru Shimosegawa, Atsushi Kanno
Mar 11, 2010·The American Journal of Gastroenterology·Terumi KamisawaTsuneo Sasaki
Jun 23, 2010·AJR. American Journal of Roentgenology·Kristina I RingeElmar M Merkle
Aug 25, 2010·Advances in Anatomic Pathology·Wah Cheuk, John K C Chan
Oct 4, 2011·Journal of Clinical Imaging Science·Francesca Fornasa
Oct 24, 2013·AJR. American Journal of Roentgenology·Kumaresan SandrasegaranGregory A Cote
Aug 12, 2014·European Radiology·Riccardo NegrelliRoberto Pozzi Mucelli

❮ Previous
Next ❯

Citations

Jun 24, 2016·AJR. American Journal of Roentgenology·Seo-Youn Choi, Seong Hyun Kim
Jun 24, 2016·AJR. American Journal of Roentgenology·Binit Sureka, Kalpana Bansal
May 17, 2017·Polish journal of radiology·Binit Sureka, Archana Rastogi
Dec 1, 2017·The Cancer Journal·Linda C ChuElliot K Fishman
Nov 6, 2018·Journal of the Belgian Society of Radiology·Seung Soo KimSung Shick Jou
Sep 29, 2019·Abdominal Radiology·Kunal KothariFrank H Miller
Sep 8, 2019·Abdominal Radiology·Camila Lopes VendramiFrank H Miller
Oct 28, 2019·Abdominal Radiology·Ashish KhandelwalNaoki Takahashi
Apr 18, 2020·Abdominal Radiology·Yanqiu ZhengAyman H Gaballah
Mar 11, 2020·Frontiers in Physiology·Lixia WangDebiao Li
Jun 20, 2020·United European Gastroenterology Journal·J-Matthias LöhrUNKNOWN UEG guideline working group
Jul 25, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Wolfgang SchimaHelmut Kopf
Apr 17, 2020·Japanese Journal of Radiology·Masaaki TakahashiUNKNOWN Working Group Members of The Research Program on Intractable Diseases from the Ministry of Labor, Welfare of Japan
Jan 8, 2020·International Journal of Molecular Sciences·Hiroyuki MatsubayashiHiroyuki Ono
Apr 27, 2018·Insights Into Imaging·Christopher Siew Wai TangNyree Griffin
Nov 23, 2019·Clinical Imaging·W James TomLejla Aganovic
Mar 25, 2021·AJR. American Journal of Roentgenology·Liang ZhuYamin Lai
Oct 27, 2021·Journal of Medical Ultrasonics·Hiroshi OgawaShinji Naganawa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.