Abstract
We have demonstrated in previous studies that DNA image cytometry (DNA ICM) can be helpful in detecting malignancy in sebaceous tumours of the Muir-Torre syndrome and sweat gland tumours. However, little is known about DNA ICM in cutaneous adnexal tumours with follicular differentiation. To study a larger series of benign and malignant follicular adnexal tumours with DNA ICM. We studied 13 malignant follicular tumours (seven trichilemmal carcinomas, five malignant proliferating pilar tumours, one pilomatrix carcinoma) and 55 benign follicular tumours (four tumours of the follicular infundibulum, seven Winer's pores, eight trichilemmomas, two trichofolliculomas, 16 trichoepitheliomas, 13 pilomatrixomas, five trichoblastomas) by DNA ICM. All cases were clear-cut as malignant or benign, respectively, on histopathological criteria. The stemline interpretation according to Böcking et al. (DNA distribution in gastric cancer and dysplasia. In: Precancerous Conditions and Lesions of the Stomach, Zhang YC, Kawai K, eds. Berlin: Springer-Verlag, 1993: 103-20) was performed in all cases. In addition, 5[c]-exceeding events (5cEE) and the 2[c] deviation index (2cDI) were calculated, except in one histopathologically benign tumour, which rev...Continue Reading
References
Nov 1, 1992·Histopathology·G N RuttyJ H Laing
May 1, 1992·Archives of Dermatology·A J Herzberg
Feb 1, 1991·Journal of Cutaneous Pathology·A J MarrogiL P Dehner
Jul 1, 1990·Journal of the American Academy of Dermatology·M S RabkinV Y Soong
Feb 1, 1990·The Journal of Investigative Dermatology·W StolzG Burg
Jun 1, 1988·The American Journal of Dermatopathology·R Jaworski
Oct 1, 1995·The British Journal of Dermatology·S BiesterfeldA Böcking
May 1, 1996·Human Pathology·C Cohen
Jan 1, 1995·Journal of Cellular Biochemistry. Supplement·B PalcicC E MacAulay
May 1, 1997·Journal of Cutaneous Pathology·P KiehlA Bocking
Jan 1, 1997·Dermatology : International Journal for Clinical and Investigative Dermatology·F DragoA Rebora
Jan 1, 1997·Dermatology : International Journal for Clinical and Investigative Dermatology·G NotoM Aricò
Mar 21, 1998·Cancer·D D DaveyH Gallion
Jun 26, 1998·The British Journal of Dermatology·P KiehlA Böcking
Dec 31, 1998·Histopathology·J HerreroA Llombart-Bosch
Jul 3, 1999·Analytical Cellular Pathology : the Journal of the European Society for Analytical Cellular Pathology·G HaroskeA Böcking
Nov 17, 1999·Histopathology·G Noto
May 3, 2000·The British Journal of Dermatology·M VogelbruchP Kiehl
Citations
Aug 19, 2011·Plant Cell Reports·Milene Miranda Praça-FontesWellington Ronildo Clarindo
Apr 7, 2007·The American Journal of Dermatopathology·Omer GünhanUğur Berberoğlu
Oct 19, 2004·American Journal of Clinical Pathology·Jay YeMark R Wick
Apr 22, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Emily TierneyTeresa T Soriano
Oct 21, 2004·Cancer·Adem ElzagheidYrjo Collan
Dec 21, 2004·Journal of Cutaneous Pathology·Alexander J F LazarPhillip H McKee