Differentiation between pancreatic metastases from renal cell carcinoma and hypervascular neuroendocrine tumour: Use of relative percentage washout value and its clinical implication

European Journal of Radiology
Tae Wook KangMin Ji Kim

Abstract

To compare computed tomography (CT) findings in patients with pancreatic metastasis from renal cell carcinoma (pRCC) and patients with hypervascular pancreatic neuroendocrine tumour (pNET) with a focus on the relative percentage washout (RPW). We evaluated 16 patients with 37 pRCCs and 28 patients with 31 hypervascular pNETs using a protocol consisting of arterial and portal phase CT. Imaging findings were analyzed for comparison between the two groups. The RPW of each tumour using biphasic CT was obtained by two observers for evaluation of diagnostic performance. Interobserver agreement of each value and optimal cut-off level of RPW for discrimination between groups were evaluated. Tumour multiplicity showed significant difference in both groups. The mean RPW of the pRCC group (observer 1, 27.0%; observer 2, 29.4%) was significantly higher than that of the pNET group (observer 1, 0.5%; observer 2, 3.2%) (p<0.001 for each observer). Interobserver agreement for both attenuation values and RPWs was excellent. A RPW value of 19% was selected as the optimal cut-off for pRCC determination, and showed good performance (accuracy 83.8%, sensitivity 83.8%, and specificity 83.9%). With multiplicity, RPW of the tumour on CT could be helpf...Continue Reading

References

Jan 1, 1997·European Radiology·F FerrozziP Bassi
Apr 16, 1998·Radiographics : a Review Publication of the Radiological Society of North America, Inc·K A KleinT J Welch
Jun 1, 1999·AJR. American Journal of Roentgenology·C S NgC Charnsangavej
Aug 30, 2000·Cancer·L D Thompson, C S Heffess
Feb 28, 2002·Radiology·Elaine M CaoiliKartik I Raghupathi
Aug 23, 2003·AJR. American Journal of Roentgenology·J L FidlerF J Service
Oct 7, 2003·Annals of Surgical Oncology·Calvin H L LawSteven Gallinger
Sep 16, 2005·Biometrical Journal. Biometrische Zeitschrift·Ronen FlussBenjamin Reiser
Apr 17, 2007·European Journal of Radiology·Sung Eun RhaJae Mun Lee
Jul 25, 2007·AJR. American Journal of Roentgenology·Nyree GriffinS Aslam Sohaib
Jan 16, 2008·Annals of Surgical Oncology·Alessandro ZerbiValerio Di Carlo
Apr 12, 2008·Abdominal Imaging·Sandra MechóCarmen Sebastià
Jan 9, 2010·European Journal of Radiology·Hye Young SunByung Ihn Choi
Jul 20, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Gavin LowEdward Leen
Dec 8, 2011·World Journal of Gastroenterology : WJG·Roberto BallarinFabrizio Di Benedetto
Jul 25, 2012·AJR. American Journal of Roentgenology·Siva P RamanElliot K Fishman
Nov 13, 2012·Langenbeck's Archives of Surgery·F M WatzkaT J Musholt
Jun 1, 2014·Annals of Surgical Oncology·L SchwarzJ J Tuech
Jul 1, 2014·World Journal of Gastroenterology : WJG·Eun Sun Lee, Jeong Min Lee

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Citations

Jun 15, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Alberto Diaz de LeonIvan Pedrosa
Oct 22, 2020·Japanese Journal of Radiology·Marion BartoliPhilippe Soyer
Dec 7, 2019·Seminars in Ultrasound, CT, and MR·Marco Dioguardi BurgioValérie Vilgrain
Jul 21, 2021·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Kunio KataokaMitsuhiro Fujishiro

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