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Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes

Differentiation; Research in Biological Diversity

Jul 20, 2005

Jacqueline T HechtDaniel D Carson

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Abstract

An exostosis or osteochondroma is an aberrant bony growth occurring next to the growth plate either as an isolated growth abnormality or as part of the Hereditary Multiple Exostosis (HME) syndrome. Mutations in either exostosin 1 (EXT1) or exostosin 2 (EXT2) gene cause the HME syndrome ...read more

Mentioned in this Paper

Exostoses
Golgi Apparatus
Glycosaminoglycans
Proteoglycan
Chondrocyte Differentiation
Hereditary Multiple Exostoses
N-Acetylglucosaminyltransferases
Mucopolysaccharidosis III
Chondrocyte
Cell Differentiation Process
Paper Details
References
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  • Citations25
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  • References45
  • Citations25
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Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes

Differentiation; Research in Biological Diversity

Jul 20, 2005

Jacqueline T HechtDaniel D Carson

PMID: 16026543

DOI: 10.1111/j.1432-0436.2005.00025.x

Abstract

An exostosis or osteochondroma is an aberrant bony growth occurring next to the growth plate either as an isolated growth abnormality or as part of the Hereditary Multiple Exostosis (HME) syndrome. Mutations in either exostosin 1 (EXT1) or exostosin 2 (EXT2) gene cause the HME syndrome ...read more

Mentioned in this Paper

Exostoses
Golgi Apparatus
Glycosaminoglycans
Proteoglycan
Chondrocyte Differentiation
Hereditary Multiple Exostoses
N-Acetylglucosaminyltransferases
Mucopolysaccharidosis III
Chondrocyte
Cell Differentiation Process

Feeds With Similar Papers

Osteochondroma

Osteochondromas involve an overgrowth of catilage and bone. Here is the latest research on osteochondromas.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes(opens in new tab)

Proceedings of the National Academy of Sciences of the United States of AmericaJanuary 19, 2010
Kevin B JonesVal C Sheffield
Paper Details
References
  • References45
  • Citations25
12345
  • References45
  • Citations25
123

Download from

Publisher
PubMed
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