Differentiation measures for conservation genetics

Evolutionary Applications
Lou JostEmily Latch

Abstract

We compare the two main classes of measures of population structure in genetics: (i) fixation measures such as FST,GST, and θ and (ii) allelic differentiation measures such as Jost's D and entropy differentiation. These two groups of measures quantify complementary aspects of population structure, which have no necessary relationship with each other. We focus especially on empirical aspects of population structure relevant to conservation analyses. At the empirical level, the first set of measures quantify nearness to fixation, while the second set of measures quantify relative degree of allelic differentiation. The two sets of measures do not compete with each other. Fixation measures are often misinterpreted as measures of allelic differentiation in conservation applications; we give examples and theoretical explanations showing why this interpretation can mislead. This misinterpretation has led to the mistaken belief that the absolute number of migrants determines allelic differentiation between demes when mutation rate is low; we show that in the finite island model, the absolute number of migrants determines nearness to fixation, not allelic differentiation. We show that a different quantity, the factor that controls Jost'...Continue Reading

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Citations

Apr 25, 2020·Integrative Zoology·Berta Capellà MarzoIñigo Martínez-Solano
Jul 22, 2018·Evolutionary Applications·Margaret E HunterLouis Bernatchez
May 3, 2019·Scientific Reports·Patricia María Rodríguez-GonzálezMaria Helena Almeida
Nov 7, 2019·BMC Evolutionary Biology·Margaret L HainesEmily K Latch
Oct 2, 2019·Frontiers in Genetics·Eugenio López-CorteganoArmando Caballero
Feb 18, 2021·PloS One·Kefyalew NegishoGwendolin Wehner
Mar 20, 2021·Vavilovskiĭ Zhurnal Genetiki I Selekt︠s︡ii·V R Kharzinova, N A Zinovieva
Nov 6, 2018·Microbiology Spectrum·Ronald E Blanton
Sep 30, 2021·Proceedings. Biological Sciences·Giulia Francesca Azzurra DonatiLoïc Pellissier

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