Differentiation of hepatic tumors by color Doppler imaging: role of the maximum velocity and the pulsatility index of the intratumoral blood flow signal

Intervirology
M KudoPei Zhou

Abstract

Doppler spectral analysis using color Doppler ultrasonography (US) was performed in a total of 133 patients with 135 hepatic tumors, including 88 hepatocellular carcinomas (HCCs), 30 metastatic hepatic cancers, 15 hemangiomas and 2 focal nodular hyperplasias (FNHs). Mean +/- SD of maximum velocity (Vmax) in hemangiomas (15.0 +/- 16.0 cm/s) was significantly lower than in HCCs (34.9 +/- 26.7 cm/s) and in metastases (37.9 +/- 17.4 cm/s). Mean +/- SD of the pulsatility index (PI) in hemangiomas (0.45 +/- 0.41) was significantly lower than in HCCs (1.52 +/- 0.71) and metastases (1.44 +/- 0.43). Mean +/- SD of Vmax and PI in FNH was 20.0 +/- 11.3 cm/s and 0.90 +/- 0.35, respectively. HCC showed a wide spectrum in terms of Vmax and PI; however, 18% of the HCC nodules had relatively high PI (>2.0). Specificity of Vmax more than >60 cm/s and PI more than 2.0 for the diagnosis of HCC were 92 and 94%, respectively. On the other hand, 87% of hemangiomas showed relatively lower Vmax (<30 cm/s) and 87% of hemangiomas showed relatively low PI (<1.0 cm/s). Specificity of Vmax less than 30 cm/s and PI less than 1.0 for the diagnosis of hemangioma were 47 and 78%, respectively. When taking account of both parameters, Vmax and PI, diagnostic eff...Continue Reading

Citations

Feb 20, 2009·Journal of Gastroenterology·Masatoshi Kudo
Sep 20, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Fabio Piscaglia, Luigi Bolondi

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