Differentiation of periapical granulomas and cysts by using dental MRI: a pilot study

International Journal of Oral Science
Alexander JuerchottTim Hilgenfeld

Abstract

The purpose of this pilot study was to evaluate whether periapical granulomas can be differentiated from periapical cysts in vivo by using dental magnetic resonance imaging (MRI). Prior to apicoectomy, 11 patients with radiographically confirmed periapical lesions underwent dental MRI, including fat-saturated T2-weighted (T2wFS) images, non-contrast-enhanced T1-weighted images with and without fat saturation (T1w/T1wFS), and contrast-enhanced fat-saturated T1-weighted (T1wFS+C) images. Two independent observers performed structured image analysis of MRI datasets twice. A total of 15 diagnostic MRI criteria were evaluated, and histopathological results (6 granulomas and 5 cysts) were compared with MRI characteristics. Statistical analysis was performed using intraclass correlation coefficient (ICC), Cohen's kappa (κ), Mann-Whitney U-test and Fisher's exact test. Lesion identification and consecutive structured image analysis was possible on T2wFS and T1wFS+C MRI images. A high reproducibility was shown for MRI measurements of the maximum lesion diameter (intraobserver ICC = 0.996/0.998; interobserver ICC = 0.997), for the "peripheral rim" thickness (intraobserver ICC = 0.988/0.984; interobserver ICC = 0.970), and for all non-qua...Continue Reading

References

Apr 1, 1989·Endodontics & Dental Traumatology·M TropeL Tronstad
Feb 1, 1973·Oral Surgery, Oral Medicine, and Oral Pathology·D R MorseG R Schacterle
Jul 1, 1968·Oral Surgery, Oral Medicine, and Oral Pathology·C J Cunningham, E C Penick
Jan 1, 1984·Oral Surgery, Oral Medicine, and Oral Pathology·E NatkinL I Carnes
Nov 1, 1980·Journal of Endodontics·J H Simon
Nov 1, 1994·Oral Surgery, Oral Medicine, and Oral Pathology·S C WhiteN J Mankovich
Jan 1, 1996·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·P N Ramachandran NairH E Schroeder
May 13, 1999·International Endodontic Journal·P N Nair
Mar 17, 2000·Journal of Neuro-oncology·P D SchellingerA Thron
Jul 12, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Mark A GriswoldAxel Haase
Jul 30, 2003·Journal of Dental Research·F ShafieiT Sasaki
Sep 1, 1954·Oral Surgery, Oral Medicine, and Oral Pathology·W A PRIEBEA H WUEHRMANN
Nov 10, 2004·Dento Maxillo Facial Radiology·B KressK Sartor
Dec 3, 2004·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·P N R Nair
Mar 1, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Domenico RicucciThomas R Pitt Ford
Feb 13, 2008·Clinical Oral Implants Research·Marcelo F AguiarMarcelo G P Cavalcanti
Apr 12, 2008·AJNR. American Journal of Neuroradiology·E Y KimY-H Ko
May 28, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·John B Ludlow, Marija Ivanovic
Apr 18, 2009·Dento Maxillo Facial Radiology·R ScharaU Skaleric
May 5, 2009·Journal of Endodontics·Malte SchulzDieter Bosshardt
Jul 2, 2009·Journal of Endodontics·Mahmoud TorabinejadShahrokh Shabahang
Jul 27, 2011·Journal of Endodontics·Djaudat IdiyatullinDonald R Nixdorf
Aug 25, 2011·AJR. American Journal of Roentgenology·Brian A HargreavesGarry E Gold
Nov 22, 2011·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Domenico RicucciLarz S W Spångberg
Dec 12, 2012·Journal of Endodontics·Johannes MenteThorsten Pfefferle
Apr 24, 2013·Dento Maxillo Facial Radiology·O TymofiyevaP M Jakob
Jan 17, 2015·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·M A GeibelV Rasche
Jul 15, 2015·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Alexandre T AssafReinhard E Friedrich
Nov 10, 2015·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Marcel PragerChiara Gaudino
Mar 30, 2016·Scientific Reports·Ute LudwigJan-Bernd Hövener
Jul 13, 2017·European Radiology·Tim HilgenfeldSabine Heiland
Jun 8, 2018·ORAL & Implantology·F GrecchiF Carinci

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Citations

Sep 10, 2020·Clinical Implant Dentistry and Related Research·Florian Andreas ProbstMonika Probst
Aug 14, 2020·Clinical Oral Investigations·Christoph RoserAlexander Juerchott
Oct 14, 2020·Acta Odontologica Scandinavica·Casper KruseLise-Lotte Kirkevang
Oct 18, 2020·International Journal of Environmental Research and Public Health·Jonas ConradMohamed Mekhemar
Nov 18, 2020·Dento Maxillo Facial Radiology·Tabea FlüggeKatja Nelson
Mar 29, 2021·Journal of Endodontics·Wadim LeontievThomas Connert

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Methods Mentioned

BETA
biopsy
X-ray

Software Mentioned

SPSS
DICOM Imaging
Osirix

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