Differentiation of seminomatous from nonseminomatous testicular tumors with MR imaging

AJR. American Journal of Roentgenology
J O JohnsonJ Phillipson

Abstract

Distinguishing seminomatous from nonseminomatous testicular neoplasms preoperatively is useful because treatment of these two tumors types is different. We evaluated whether the distinction could be made with MR imaging in six patients with seminomatous and nine patients with nonseminomatous testicular tumors (including teratoma, teratocarcinoma, embryonal cell, and choriocarcinoma). The MR diagnoses, which were obtained from the formal reports of the MR studies done and interpreted before orchiectomy, were compared with the pathologic diagnosis. The distinction between the two tumor types on MR images was based on the signal intensity and heterogeneity of the lesion. We also retrospectively compared the MR findings with tissue histology. MR scans in nonseminomatous tumors showed a marked heterogeneous mix of signals, with some regions less intense and others more intense than normal testicular tissue on both proton-density and T2-weighted images. The typical background signal was nearly equal to normal testicular tissue. The tumors also had a dark band at their periphery that correlated with a fibrous tumor capsule on histologic examination. In contradistinction, seminomatous tumors were isointense with testis on proton-densit...Continue Reading

Citations

Jan 1, 1993·Seminars in Roentgenology·M Schnall
Jan 1, 1994·Clinical Oncology : a Journal of the Royal College of Radiologists·M P Williams, C A Roobottom
Mar 1, 2012·Asian Journal of Andrology·Athina C TsiliKonstantinos Tsampoulas
Sep 13, 2006·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·P U DalalR Huddart
Nov 22, 2007·AJR. American Journal of Roentgenology·Athina C TsiliStavros C Efremidis
Feb 23, 2010·AJR. American Journal of Roentgenology·Athina C TsiliKonstantine Tsampoulas
Feb 26, 2013·AJR. American Journal of Roentgenology·Athina C TsiliKonstantinos Tsampoulas
Jul 23, 2005·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Waka SaitoAtsuko Heshiki
Jun 23, 2006·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Alejandro Vara CastrodezaMiguel Angel de la Fuente Bobillo
Sep 18, 2012·Wiener klinische Wochenschrift·Guner SonmezMuzaffer Saglam
May 1, 1997·Journal of Computer Assisted Tomography·M EssigG van Kaick
May 1, 1994·Journal of Magnetic Resonance Imaging : JMRI·C Müller-LeisseR W Günther
Apr 9, 1998·Critical Reviews in Diagnostic Imaging·M J GeraghtyD J Yandow
May 6, 2014·Magnetic Resonance Imaging Clinics of North America·Seyed Mahdi AbtahiSandeep S Hedgire
May 6, 2014·Magnetic Resonance Imaging Clinics of North America·Athina C TsiliMaria I Argyropoulou
Oct 23, 2015·Polish journal of radiology·Ahmed Mohamed AlgeballyAdham Darweesh
Jul 22, 2014·Journal of Clinical Ultrasound : JCU·Michele BertolottoLorenzo E Derchi
Jan 13, 2005·Current Problems in Diagnostic Radiology·Rahul GuptaMarco Amendola
Nov 12, 2002·Magnetic Resonance Imaging Clinics of North America·Marilyn J Siegel, Fredric A Hoffer
Jun 24, 2015·PET Clinics·Kirsten Bouchelouche, Peter L Choyke
Mar 7, 2002·Urology·Valdair MugliaPeter Leonard Cooperberg
Jun 7, 2016·Radiologic Clinics of North America·Iván R Rohena-QuinquillaDarcy Wolfman
Aug 24, 2012·AJR. American Journal of Roentgenology·Oliver K MohrsPeter Hallscheidt
Jun 3, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jamie MarkoIsabell A Sesterhenn
Aug 5, 1993·The New England Journal of Medicine·J F Kennedy
Nov 6, 2018·Abdominal Radiology·Athina C TsiliMaria I Argyropoulou
Jul 13, 2017·European Radiology·Athina C TsiliJonathan Richenberg
May 9, 2021·Andrology·Athina C TsiliLucia Manganaro

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.