Differentiation of the phenolic chemical profiles of Cecropia pachystachya and Cecropia hololeuca

Phytochemical Analysis : PCA
Marcelo da Silva Mathias, Rodrigo Rodrigues de Oliveira

Abstract

Cecropia pachystachya and C. hololeuca are common species in Brazil, popularly used to treat respiratory diseases. Phytochemical studies indicate that their leaves are rich in phenolic compounds, mainly C-glycosilated flavonoids. Orientin and isoorientin are reported in both species, while vitexina and isovitexina were reported in C. pachystachya. In addition, both are rich in chlorogenic acid and have some procyanidins. In some cases, syrups and teas are prepared from leaf blends from different species, which may affect the efficacy and safety of this natural medication. This problem motivated the investigation of the chemical profile of leaves of these species. The phenolic chemical profiles from C. pachystachya and C. hololeuca methanolic extracts were analysed by ultra-high performance liquid chromatography coupled with a diode array detector and mass spectrometry (UPLC-DAD-MS), to investigate possible differences in their metabolite production. The methanolic extracts of both species were analysed by UPLC-DAD-MS using a C-18 reverse phase column, DAD at 190-400 nm and electrospray ionisation quadruple time-of-flight (ESI-Q-TOF) mass spectrometer. The separation methodology was validated and most of the flavones present in ...Continue Reading

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Citations

Aug 10, 2020·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Henrique Herbst RosaIzabella Thaís Silva

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