Differentiation of the vertebrate neural tube

Current Opinion in Cell Biology
M Bronner-Fraser, S E Fraser

Abstract

The vertebrate nervous system arises through a series of inductive interactions, beginning with the induction of the neural plate and the rostrocaudal patterning of the neural tube. The process continues with dorsoventral patterning of the neural tube, during which floor plate cells and motor neurons are induced ventrally by interactions of the neural tube with the notochord, and dorsal cell types are induced via neural plate/ectodermal interactions. Later interactions result in the formation of interneurons as well as neuronal migrations. Recent progress, guided in part by knowledge of evolutionary conservation of transcription factors and signaling pathways, is beginning to reveal the cellular and molecular bases of each of these steps in neuronal patterning.

References

Aug 1, 1995·Developmental Dynamics : an Official Publication of the American Association of Anatomists·J E VarleyG D Maxwell
Jul 27, 1995·Nature·P A Wilson, A Hemmati-Brivanlou
Apr 1, 1994·Mechanisms of Development·M L DirksenM Jamrich
Oct 29, 1993·Science·T M LambR M Harland
Nov 15, 1996·Science·Y Tanabe, T M Jessell
Jan 1, 1997·Annual Review of Cell and Developmental Biology·R Harland, J Gerhart

❮ Previous
Next ❯

Citations

Dec 22, 2005·Pediatric Surgery International·Parkash MandhanMichael Sullivan
Feb 3, 2012·The Journal of Biological Chemistry·Maud ForsbergKarin Forsberg-Nilsson
Jul 1, 1999·Genes & Development·H TakahashiN Satoh
Apr 8, 2011·Development·Wei LiuRaymond Habas
Jun 5, 2004·Neuroimaging Clinics of North America·Ruby J LienBradley N Delman
Mar 11, 2000·Journal of Receptor and Signal Transduction Research·S C ChenR J Smeyne
Feb 18, 1999·Current Biology : CB·M MuroneF J de Sauvage
Oct 18, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·M Mina
Mar 29, 2000·The Journal of Biological Chemistry·S Mouillet-RichardO Kellermann
Apr 4, 2000·Physiological Reviews·J C ReklingJ L Feldman
Nov 8, 2002·Development·John B Wallingford, Richard M Harland

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.