Difficult and complex separation from cardiopulmonary bypass in high-risk cardiac surgical patients: a multicenter study

Journal of Cardiothoracic and Vascular Anesthesia
André Y DenaultBART Investigators

Abstract

To determine the impact of the pharmacologic and mechanical support required during separation from cardiopulmonary bypass (CPB) on survival after cardiac surgery. The authors hypothesized that difficulty with separation from CPB was associated independently with life-threatening complications and survival after cardiac surgery. Prospective study. Nineteen tertiary care hospitals involved in the Blood Conservation Using Antifibrinolytics in a Randomized Controlled Trial (BART). High-risk cardiac surgical patients. Separation from CPB was stratified as easy when no support or only one vasoactive agent or inotrope was required, difficult or pharmacologically assisted when the 2 drug types were used, and complex when the first weaning process failed or the patient required mechanical devices to be weaned from CPB. These definitions were based on a retrospective analysis of 6,120 consecutive cardiac surgical patients who underwent cardiac surgery in a single center. Backward logistic regression was performed to determine predictors of life-threatening complications and mortality. There were 2,331 patients with a mean age of 66 ± 11 years, and 71.8% were men. There were 1,158 (49.7%), 835 (35.8%) and 338 (14.5%) patients in the easy...Continue Reading

References

Jun 1, 1993·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·J F HardyJ Perrault
Jul 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·V RaoT E David
Mar 12, 1998·Anesthesia and Analgesia·J F ButterworthJ W Hammon
Aug 4, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F RoquesL Thulin
Apr 6, 2000·The Annals of Thoracic Surgery·A D Bernstein, V Parsonnet
Feb 28, 2001·Anesthesia and Analgesia·S D SurgenorUNKNOWN Northern New England Cardiovascular Disease Study Group
Sep 15, 2004·Journal of Cardiothoracic and Vascular Anesthesia·Kenneth H McKinlayJoseph P Mathew
Jan 20, 2006·European Heart Journal·Johan NilssonJohan Brandt
Jan 24, 2006·The Annals of Thoracic Surgery·Marius BermanAlexander Kogan
Jun 6, 2006·Journal of Cardiothoracic and Vascular Anesthesia·Arnaud RobitailleRaymond Martineau
Jun 15, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·François HaddadJean-Claude Tardif
Mar 22, 2008·The Annals of Thoracic Surgery·Lorenzo MerelloBernhard Westerberg
May 16, 2008·The New England Journal of Medicine·Dean A FergussonUNKNOWN BART Investigators
Jul 27, 2010·Seminars in Cardiothoracic and Vascular Anesthesia·André Y DenaultPierre Couture

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Citations

Mar 26, 2013·Journal of Cardiothoracic and Vascular Anesthesia·André Y DenaultAndrea M D'Armini
Jun 12, 2016·Journal of Critical Care·Tanya MailhotAndré Y Denault
Jul 15, 2015·American Journal of Respiratory and Critical Care Medicine·Alain CombesCharles-Edouard Luyt
May 16, 2015·Journal of Cardiothoracic and Vascular Anesthesia·André Y DenaultJean Lambert
Dec 3, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Maxime LaflammeAndré Y Denault
Jul 30, 2016·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·André Y DenaultJean Lambert
Feb 15, 2014·Seminars in Cardiothoracic and Vascular Anesthesia·Karsten BartelsG Burkhard Mackensen
Dec 14, 2012·Current Opinion in Anaesthesiology·André Yvan DenaultAlain Deschamps
Feb 27, 2020·Expert Review of Medical Devices·Joseph Lamelas, Ahmed Alnajar
Sep 19, 2019·Journal of Cardiothoracic and Vascular Anesthesia·Suneel Ramesh Desai, Nian Chih Hwang

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