Diffuse alveolar hemorrhage with predominantly right-sided infiltration resulting from cardiac comorbidities

Internal Medicine
Koji TamaiKazuma Nagata

Abstract

Radiographic findings in patients with diffuse alveolar hemorrhage (DAH) are usually diffuse and bilateral, although they may occasionally be unilateral. The clinical aspects of predominantly unilateral DAH are not well known. Therefore, our objective was to describe the clinical characteristics of predominantly right-sided DAH. We retrospectively reviewed data for 460 bronchoalveolar lavage fluid (BALF) samples collected between January 2009 and July 2013. Patients who presented with increasingly hemorrhagic BALF were diagnosed with DAH, and unilateral predominance was determined based on the degree of infiltration on chest radiographs. The records of 54 patients with DAH were evaluated. The leading etiology was pulmonary congestion due to heart failure (n=15). The radiographs showed right-sided infiltration in 18 patients (33%), left-sided infiltration in six patients (11%) and bilateral infiltration in 30 patients (56%). Predominantly right-sided DAH was often caused by pulmonary congestion resulting from heart failure (10 of 18 patients). A multivariate logistic regression analysis revealed a previous history of cardiovascular disease to be the only significant predictor of right-sided DAH (OR 13.1, 95% CI 2.9-95.4). Predom...Continue Reading

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Citations

Mar 5, 2016·Journal of Nephrology·Luca ViscontiAntonio Lacquaniti
Sep 8, 2019·Current Rheumatology Reports·Sarah Abramson StootsDoruk Erkan
Sep 7, 2016·Ultrasound Quarterly·Natalia BudaZbigniew Zdrojewski
May 21, 2020·Acute Medicine & Surgery·Ayaka SakamotoYoshiaki Inoue
Mar 13, 2021·Lung·Biplab K Saha, Woon H Chong
Apr 22, 2021·American Journal of Respiratory and Critical Care Medicine·Akihito OkazakiKazuhiko Shibata

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