Diffuse idiopathic skeletal hyperostosis: diagnosis in a palaeopathological context

Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen
A E van der MerweI Watt

Abstract

Clinically, the presence of diffuse idiopathic skeletal hyperostosis (DISH) has been linked to a disturbance of glucose and insulin metabolism, hypertension, dyslipidemia and obesity associated with a rich diet. The prevalence of DISH in archaeological skeletal samples may therefore be a valuable indicator of their socio-economic status when compared to other contemporary groups. However, various methods are currently being used to diagnose DISH. The purpose of this study was therefore to assess the comparability of results obtained using four different diagnostic methods to estimate the prevalence of DISH in a skeletal sample, and to discuss the implications of the results in relation to palaeopathological health assessments. Four different diagnostic criteria were applied to 127 male and 113 female skeletons to diagnose DISH. Skeletal remains were obtained from two 16th century samples from Delft and one modern sample from the anatomy dissection hall of the Leiden University Medical Centre. The estimated prevalences were statistically compared. Special attention was also given to the distribution of extra-spinal enthesophytes described in diagnostic criteria, in order to assess their diagnostic value. The prevalence of DISH o...Continue Reading

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Citations

Nov 6, 2013·Nature Reviews. Rheumatology·Reuven MaderDan Buskila
Apr 10, 2013·Joint, Bone, Spine : Revue Du Rhumatisme·Bernard Mazières
Mar 24, 2016·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·R L V Holgate, M Steyn
Jan 20, 2015·The Open Rheumatology Journal·Sruti Pillai, Geoffrey Littlejohn
Apr 4, 2017·Rheumatology·Jonneke S KuperusJorrit-Jan Verlaan

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