PMID: 20647652Jul 22, 2010Paper

Diffuse liver metastasis of small cell lung cancer causing marked hepatomegaly and fulminant hepatic failure

Internal Medicine
Hisamitsu MiyaakiKazuhiko Nakao

Abstract

A 62-year-old female was admitted for examination of an abnormal liver function. Plain CT and MRI of the abdomen showed marked hepatomegaly but no visible nodular lesion in the liver. On the 3rd hospital day she had hepatic encephalopathy and was treated with a course of high-dose steroids, but ultimately died of disease progression on the 7th hospital day. An autopsy revealed a small pulmonary nodule with the histological findings showing small cell carcinoma. There was almost complete parenchymal replacement with metastatic tumor in the liver. Neoplastic involvement of the liver should be considered in the differential diagnosis of fulminant hepatic failure of unknown etiology.

References

Aug 1, 1986·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A F ListD H Johnson
May 1, 1986·Seminars in Liver Disease·J BernuauJ P Benhamou
Oct 16, 2003·European Journal of Gastroenterology & Hepatology·Elias AthanasakisDimitrios Georgopoulos
Mar 11, 2005·Journal of Clinical Gastroenterology·Pankaj RajvanshiEmmet B Keeffe
Feb 22, 2008·Clinical Nuclear Medicine·Faizatul I RozalliDesmond J Green

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Citations

Dec 1, 2012·Archives of Pathology & Laboratory Medicine·Larry NicholsFriedrich D Knollmann
Oct 2, 2012·Journal of Postgraduate Medicine·P VaideeswarK Deodhar
Jan 1, 2013·Mayo Clinic Proceedings·Jasmine Riviere MarcelinBrian A Costello
Apr 5, 2016·Case Reports in Critical Care·Varalaxmi Bhavani NannakaDmitry Lvovsky
Feb 1, 1997·Mayo Clinic Proceedings·B M McGuireS B Ho
Jan 1, 2017·Acta Medica (Hradec Králové)·Antigony MitselouVasiliki Galani

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