Diffuse neurofibroma--an uncommon cause of alopecia

Anais Brasileiros De Dermatologia
Vasco Coelho MaciasJoaninha Costa Rosa

Abstract

Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.

References

Oct 1, 1994·The American Journal of Dermatopathology·M Megahed
Feb 1, 1996·The Journal of Laryngology and Otology·S J de VarebekeP H Van de Heyning
Nov 17, 1998·Clinical Radiology·I BeggsR M Davie
Mar 4, 2000·Plastic and Reconstructive Surgery·S S ErgünN Büyükbabani
Jun 6, 2003·Journal of the American Academy of Dermatology·E J van Zuuren, A N Posma
Apr 28, 2005·AJR. American Journal of Roentgenology·Guo-Shu HuangCheng-Yu Chen
Feb 22, 2008·AJR. American Journal of Roentgenology·Douglass S HassellJulie C Fanburg-Smith
Feb 1, 2009·Annals of Dermatology·Kwang-Ho YooKye-Yong Song
Dec 29, 2010·International Journal of Trichology·Bc Sharath KumarM Ramesh

❮ Previous
Next ❯

Citations

Aug 2, 2014·Skeletal Radiology·Ananth K RaviTarun Pandey
Feb 27, 2020·Pediatric Dermatology·Carol Hlela, Anthony J Mancini
Oct 27, 2018·BJR Case Reports·Adenike Temitayo Adeniji-SofoluweClement Abu Okolo
Jul 14, 2020·Skin Appendage Disorders·I-Ting LeeYu Fu

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Dermatology
Kwang-Ho YooKye-Yong Song
AJR. American Journal of Roentgenology
Douglass S HassellJulie C Fanburg-Smith
AJR. American Journal of Roentgenology
Guo-Shu HuangCheng-Yu Chen
© 2021 Meta ULC. All rights reserved