Diffuse T-cell lymphoma preceded by nodular lymphoma

American Journal of Clinical Pathology
J C JennetteA S Wilkman

Abstract

A patient with a nodular lymphoma morphologically indistinguishable from follicular B-cell lymphoma subsequently developed a diffuse T-cell lymphoma. This T-cell lymphoma displayed characteristics analogous to mature T-lymphocytes, and typed as a suppressor/cytotoxic T-cell with the monoclonal antibodies. The light and electron microscopy morphology of the T-cell lymphoma was similar to that reported for node-based T-cell lymphomas. There was a polymorphous proliferation of variably transformed lymphocytes including immunoblasts. This case could represent either a nodular form of T-cell lymphoma converting to a diffuse T-cell lymphoma, or a follicular B-cell lymphoma preceding, and possibly inducing, a suppressor T-cell lymphoma.

Citations

Jan 9, 2020·Current Medical Research and Opinion·Luca Roncati
Feb 3, 1999·American Journal of Hematology·S M AnsellR L Phyliky
Jul 1, 1990·Acta Pathologica Japonica·M TokunagaK Kita

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