Diffuse Tenosynovial Giant Cell Tumor Around the Temporomandibular Joint: An Entity With Special Radiologic and Pathologic Features

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Ji-Gang WangJihua Liu

Abstract

Diffuse tenosynovial giant cell tumor (TGCT) of the temporomandibular joint (TMJ) is rare. The aim of the present study was to summarize the clinical, radiologic, and pathologic features of this tumor. Nine cases of TGCT in the TMJ region were examined. All available radiologic and pathologic documents were carefully reviewed. These cases were grouped into 3 types according to the radiologic features: bone-centered type, intraosseous type, and soft tissue type. Cases reported in the literature were reviewed to better summarize the clinical characteristics. TGCTs in the TMJ region showed some special radiologic and pathologic features. Radiologically, the lesion could be centered in the craniofacial bone or centered in the surrounding soft tissue. Four cases were categorized as the bone-centered type, 1 was categorized as the intraosseous type, and 4 were categorized as the soft tissue type. Pathologically, epithelioid mononuclear cells with abundant eosinophilic cytoplasm and eccentric nuclei were observed in all cases. Chondroid metaplasia was noted in 8 cases. Some areas were similar to giant cell reparative granuloma and chondroblastoma. All patients who underwent complete tumor resection showed no evidence of recurrence at ...Continue Reading

Citations

Jan 18, 2020·Head and Neck Pathology·Jen-Chieh Lee, Hsuan-Ying Huang
May 12, 2020·Acta otorrinolaringológica española·Mercedes Álvarez-Buylla BlancoAna Reguera Arias
Mar 18, 2021·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Yajuan J LiuEleanor Y Chen
May 1, 2021·Journal of Surgical Case Reports·Abdullah KanbourPeter Ricciardo

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