PMID: 18196624Jan 16, 2008Paper

Diffusion- and perfusion-weighted magnetic resonance imaging: possibilities and perspectives

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Z A SuslinaM A Piradov

Abstract

The article addresses theoretical and practical issues of using diffusion- (DW-MRI) and perfusion-weighted (PW-MRI) magnetic resonance tomography in acute period of ischemic stroke. The authors consider prognostic value of the results obtained with both methods of MRI-diagnosis and possibilities of their usage in pathophysiological studies of ischemic stroke. Prognostic value of DW-MRI in measuring of final size of stroke used at the first day of stroke is higher compared to standard regimes. A ratio between clinical and MRI data has been analyzed. A conception comparing a ratio between the presence of lesion and its size using DW-MRI and PW-MRI is presented. A longer duration of the penumbra comparing to conventional terms was described. The results of DW-MRI and PW-MRI study are suggested to be used for prognostic purpose as well as for elaboration of an optimal treatment tactics. Some controversial issues of using DW-MRI and PW-MRI, are discussed.

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