Diffusion MRI properties of the human uncinate fasciculus correlate with the ability to learn visual associations

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Cibu ThomasChris Baker

Abstract

The uncinate fasciculus (UF) is a cortico-cortico white matter pathway that links the anterior temporal and the orbitofrontal cortex (OFC). In the monkey, transection of the UF causes significant impairments in learning conditional visual-visual associations, while object discrimination remains intact, suggesting an important role for the UF in mediating the learning of complex visual associations. Whether this functional role extends to the human UF has not been tested directly. Here, we used diffusion tensor magnetic resonance imaging (dMRI) and behavioral experiments to examine the relation between learning visual associations and the structural properties of the human UF. In a group of healthy adults, we segmented the UF and the inferior longitudinal fasciculus (ILF) and derived dMRI measures of the structural properties of the two pathways. We also used a behavioral experiment adapted from the monkey studies to characterize the ability of these individuals to learn to associate a person's face with a group of specific scenes (conditional visual-visual association). We then tested whether the variability in the dMRI measures of the two pathways correlated with variability in the ability to rapidly learn the face-place assoc...Continue Reading

References

Dec 3, 1976·Brain Research·D A Chavis, D N Pandya
Jan 1, 1992·Trends in Neurosciences·M A Goodale, A D Milner
Jan 1, 1992·Acta neurochirurgica·U Ebeling, D von Cramon
Jul 1, 1988·The Journal of Comparative Neurology·M Petrides, D N Pandya
Nov 1, 1985·Annals of Neurology·R J Tusa, L G Ungerleider
Mar 24, 2000·Cerebral Cortex·W SchultzJ R Hollerman
May 3, 2002·The American Journal of Psychiatry·Marek KubickiMartha E Shenton
Jan 1, 1992·The European Journal of Neuroscience·M. J. Eacott, David Gaffan
Dec 19, 2002·NMR in Biomedicine·Susumu Mori, Peter C M van Zijl
Jan 4, 2003·Nature Reviews. Neuroscience·Arthur W Toga, Paul M Thompson
Feb 1, 1965·Experimental Neurology·H G KUYPERSH E ROSVOLD
Dec 20, 2003·NeuroImage·Satoru Hayasaka, Thomas E Nichols
Jan 6, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G K RohdeC Pierpaoli
Dec 22, 2005·The European Journal of Neuroscience·Philip G F BrowningDavid Gaffan
Apr 21, 2006·NeuroImage·Stephen M SmithTimothy E J Behrens
Mar 3, 2007·The American Journal of Psychiatry·Sukhwinder S ShergillPhilip McGuire
Mar 30, 2007·Brain : a Journal of Neurology·Ingrid R OlsonYoussef Ezzyat
Jul 11, 2007·Journal of the History of the Neurosciences·Jeremy D Schmahmann, Deepak N Pandya
Oct 18, 2007·Proceedings of the National Academy of Sciences of the United States of America·Marco CataniDerek K Jones
Dec 14, 2007·Proceedings of the National Academy of Sciences of the United States of America·Nikolaus KriegeskorteRainer Goebel
Apr 11, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Philip G F Browning, David Gaffan
Apr 16, 2008·Behavioral Neuroscience·Philip G F Browning, David Gaffan
Jul 16, 2008·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Marco Catani, Michel Thiebaut de Schotten
Oct 7, 2008·NeuroImage·Catherine J Stoodley, Jeremy D Schmahmann
Oct 28, 2008·Brain : a Journal of Neurology·Sumit N NiogiBruce D McCandliss

❮ Previous
Next ❯

Citations

Oct 3, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Paolo BartolomeoMarlene Behrmann
Jul 6, 2015·Developmental Cognitive Neuroscience·Ingrid R OlsonGovinda Vyas
Jun 4, 2016·Journal of Neurosurgery·Abuzer GüngörAlbert L Rhoton
Oct 22, 2016·Neuroscience and Biobehavioral Reviews·Vishnu P MurtyBeatriz Luna
Nov 16, 2017·Operative Neurosurgery·Vanessa M HolandaShabbar F Danish
Jun 25, 2017·Brain Structure & Function·Athanasia MetokiIngrid R Olson
Jul 20, 2018·The European Journal of Neuroscience·Subhojit ChakrabortyAnna S Mitchell
Apr 3, 2020·Physiological Reviews·Onur GüntürkünSebastian Ocklenburg
Nov 3, 2020·Frontiers in Psychology·Tal Dotan Ben-SoussanFilippo Carducci

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.